Immune cell Membrane‐Coated biomimetic nanoparticles for targeted cancer therapy

F Oroojalian, M Beygi, B Baradaran, A Mokhtarzadeh… - Small, 2021 - Wiley Online Library
Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …

Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Nanoparticle-modified microrobots for in vivo antibiotic delivery to treat acute bacterial pneumonia

F Zhang, J Zhuang, Z Li, H Gong, BEF de Ávila… - Nature materials, 2022 - nature.com
Bioinspired microrobots capable of actively moving in biological fluids have attracted
considerable attention for biomedical applications because of their unique dynamic features …

Enantiomer-dependent immunological response to chiral nanoparticles

L Xu, X Wang, W Wang, M Sun, WJ Choi, JY Kim… - Nature, 2022 - nature.com
Chirality is a unifying structural metric of biological and abiological forms of matter. Over the
past decade, considerable clarity has been achieved in understanding the chemistry and …

Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles

L Liu, X Bai, MV Martikainen, A Kårlund… - Nature …, 2021 - nature.com
Cell membrane coated nanoparticles (NPs) have recently been recognized as attractive
nanomedical tools because of their unique properties such as immune escape, long blood …

[HTML][HTML] Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation

Y Xiao, M Cong, J Li, D He, Q Wu, P Tian, Y Wang… - Cancer cell, 2021 - cell.com
Lung metastasis is the major cause of breast cancer-related mortality. The neutrophil-
associated inflammatory microenvironment aids tumor cells in metastatic colonization in …

Cancer cell-mitochondria hybrid membrane coated Gboxin loaded nanomedicines for glioblastoma treatment

Y Zou, Y Sun, Y Wang, D Zhang, H Yang… - Nature …, 2023 - nature.com
Glioblastoma (GBM) remains the most lethal malignant tumours. Gboxin, an oxidative
phosphorylation inhibitor, specifically restrains GBM growth by inhibiting the activity of F0F1 …

Nanozyme-reinforced hydrogel as a H2O2-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy

Y Zhao, S Song, D Wang, H Liu, J Zhang, Z Li… - Nature …, 2022 - nature.com
Stem cell-based therapy has drawn attention for enhancing the osseointegration efficiency
after joint replacement in the rheumatoid arthritis (RA). However, therapeutic efficacy of this …

Recent advances in hyperthermia therapy‐based synergistic immunotherapy

M Chang, Z Hou, M Wang, C Li, J Lin - Advanced Materials, 2021 - Wiley Online Library
The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy
against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic …

Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and nonhuman primates

QF Meng, W Tai, M Tian, X Zhuang, Y Pan, J Lai… - Science …, 2023 - science.org
Dexamethasone (DEX) is the first drug to show life-saving efficacy in patients with severe
coronavirus disease 2019 (COVID-19), while DEX is associated with serious adverse …