Neuroprognostication following acute brain injury (ABI) is a complex process that involves
integrating vast amounts of information to predict a patient's likely trajectory of neurologic …

Abstract The NLRP3 (NOD‐, LRR‐, and pyrin domain‐containing protein 3) inflammasome
is a multimeric protein complex that is engaged in the innate immune system and plays a …

Background: Increased inflammation activates blood coagulation system, higher platelet
activation plays a key role in the pathophysiology of ischemic stroke (IS). During platelet …

Ischemic stroke is a major cause of morbidity and mortality, yet lacks effective
neuroprotective treatments. The aim of this work was to investigate whether treatment with …

Abstract Xyloketal B (Xyl-B) is a novel marine compound isolated from mangrove fungus
Xylaria sp. We previously demonstrated that pretreatment with Xyl-B exerted neuroprotective …

Abstract Changes of complement and oxidative stress parameters in patients with acute
cerebral infarction (ACI) or cerebral hemorrhage (CH), and their clinical significance were …

Background CCL 23 role in the inflammatory response after acute brain injuries remains
elusive. Here, we evaluated whether CCL 23 blood levels associate with acquired cerebral …

Background Inflammation plays an important role in the pathophysiology of stroke. The aim
of the present study was to investigate the association between various inflammatory risk …

Three-dimensional (3D) spheroids composed of brain cells have shown great potential to
mimic the pathophysiology of the brain. However, a 3D spheroidal brain-disease model for …

Stroke is a common cause of physical disability. Biomarkers have been used to predict
prognosis in ischemic stroke, but studies linking biomarkers to physical recovery from …