Pathogenic fungi have many complex mechanisms of resistance to antifungal drugs.
Information about the clinical, cellular, and molecular factors contributing to antifungal-drug …

Despite significant advances in the management of immunosuppressed patients, invasive
aspergillosis remains an important life-threatening complication. In the past two decades …

The clinical signs of tinea unguium are often difficult to distinguish from those of a number of
other infectious causes of nail damage, such as Candida, mould or bacterial infection. 5 …

The series of quinoline derivatives were prepared. The synthetic approach, analytical, and
spectroscopic data of all synthesized compounds are presented. All the prepared derivatives …

Invasive candidiasis is a feared infection with mortality similar to that of septic shock (40–
60%). Improved knowledge of its pathophysiology and the availability of new compounds for …

The in vitro interaction between terbinafine and the azoles voriconazole, miconazole, and
itraconazole against five clinical Scedosporium prolificans isolates after 48 and 72 h of …

Onychomycosis is the most common nail disease encountered in clinical practice and can
cause pain, difficulty with ambulation, and psycho-social problems. A thorough history and …

Background Onychomycosis is a relatively common disease accounting for up to 50% of all
nail disorders and its prevalence rises with age. As onychomycosis is an important medical …

The development of newer antifungal drugs is creating new potential combination therapies
to combat the dismal mortality rate associated with invasive aspergillosis (IA). The efficacy of …

Background Invasive fungal diseases remain a major cause of morbidity and mortality in
cancer patients undergoing intensive cytotoxic therapy. The choice of the most appropriate …