It is now well accepted that the heart is a multifunctional organ in which endothelial cells,
and more particularly endocardial endothelial cells (EECs), seem to play an important role in …

Evidence from studies in rodents and humans support an anti-seizure action of
neuropeptide Y (NPY) in focal, acquired epilepsy. However, the effects of NPY in …

Work from our laboratory has established that angiotensin II (Ang II) produces a greater
enhancement of the nerve stimulation (NS)-induced release (overflow) of both …

Neuropeptide Y (NPY) potently suppresses absence seizures in a model of genetic
generalized epilepsy, genetic absence epilepsy rats of Strasbourg (GAERS). Here we …

Presynaptic receptors for four families of neuropeptides will be discussed: opioids,
neuropeptide Y, adrenocorticotropic hormone (ACTH), and orexins. Presynaptic receptors …

It is now well accepted that sympathetic nerves express as many as three neurotransmitters:
norepinephrine (NE), neuropeptide Y (NPY) and adenosine-5'-triphosphate (ATP)[1–4] …

We have utilized a rat model of peripheral artery disease (PAD) to examine whether the
known angiogenic activity of the Y2 receptor would translate into a meaningful increase in …

For the discovery and pharmacological characterization of new ligands of G-protein coupled
receptors, simple, robust and reliable assays are required. This thesis was aimed at the …

It is now well accepted that sympathetic nerves express as many as three neurotransmitters:
norepinephrine (NE), neuropeptide Y (NPY) and adenosine-5'-triphosphate (ATP)[1-4] …

Neuropeptide Y (NPY) is a 36-amino acid neuropeptide, abundant in the sympathetics, the
brain, and the heart. We have discovered previously that NPY is an angiogenic factor by …