Tissue sodium accumulation induces organ inflammation and injury in chronic kidney disease

Y Ito, T Sun, H Tanaka, M Yamaguchi… - International Journal of …, 2023 - mdpi.com
High salt intake is a primary cause of over-hydration in chronic kidney disease (CKD)
patients. Inflammatory markers are predictors of CKD mortality; however, the pathogenesis …

Fibroblast growth factor 21 alleviates unilateral ureteral obstruction-induced renal fibrosis by inhibiting Wnt/β-catenin signaling pathway

W Zhong, Y Jiang, H Wang, X Luo, T Zeng… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Abstract Fibroblast growth factor 21 (FGF21) is a key regulator of energy metabolism. Recent
studies suggested that serum FGF21 levels increase with declining renal function. However …

The contribution of angiotensin peptides to cardiovascular neuroregulation in health and disease

E Szczepanska-Sadowska, T Zera, M Kowara… - Angiotensin, 2023 - Elsevier
The brain renin–angiotensin system (RAS) is critically involved in the cardiovascular
regulation and energy homeostasis. The overwhelming evidence indicates that the central …