It is evident that in the last decade or so, a vast amount of new information has become
available concerning the various 5-HT receptor types and their characteristics. This derives …

Mosapride citrate is a new gastroprokinetic agent that enhances the upper GI motility by
stimulating 5-hydroxytryptamine4 (5-HT4) receptors. The purpose of this study was to …

1 The 5‐HT4 receptor has only recently been identified but has yet to be cloned. This paper
describes the pharmacology of a potent and selective 5‐HT4 receptor antagonist …

Abstract Objective: 5-HT4 receptors are present in human atrial cells and their stimulation
has been implicated in the genesis of atrial arrhythmias including atrial fibrillation. An I f-like …

1 In strips of human isolated detrusor muscle, the 5‐hydroxytryptamine (5‐HT) receptor (5‐
HT4) that mediates facilitation of neuromuscular cholinergic transmission was further …

A series of 2, 3-dihydro-2-oxo-1 H-benzimidazole-1-carboxamide derivatives bearing a
piperazine moiety was synthesized. Their in vitro 5-HT4, 5-HT3, and D2 receptors affinities …

5‐Hydroxytryptamine increases transmucosal short‐circuit current across human isolated
small intestinal mucosa. The competitive 5‐HT4 antagonist, DAU 6285 evoked a …

The effect of repeated treatment with various antidepressant drugs on the reactivity of CA1
neurons to the 5-HT 4 receptor agonist zacopride was examined. Zacopride decreased the …

Application of 5‐hydroxytryptamine induces contraction of longitudinal muscle strips from
human terminal ileum. The response was resistant to antagonism by ketanserin …

The aim of this study was to characterise the 5-HT receptor (s) mediating secretory
responses of isolated human colonic mucosa to 5-HT. Sheets of muscle-stripped mucosa …