CRISPR–Cas systems provide resistance against foreign mobile genetic elements and have
a wide range of genome editing and biotechnological applications. In this Review, we …

Genome editing technologies operate by inducing site-specific DNA perturbations that are
resolved by cellular DNA repair pathways. Products of genome editors include DNA breaks …

Base editors have substantial promise in basic research and as therapeutic agents for the
correction of pathogenic mutations. The development of adenine transversion editors has …

For centuries, cannabis has been a rich source of fibrous, pharmaceutical, and recreational
ingredients. Phytocannabinoids are the most important and well-known class of cannabis …

The rediscovery of Mendel's work showing that the heredity of phenotypes is controlled by
discrete genes was followed by the reconciliation of Mendelian genetics with evolution by …

Most short sequences can be precisely written into a selected genomic target using prime
editing; however, it remains unclear what factors govern insertion. We design a library of …

The clustered regularly interspaced short palindromic repeats (CRISPR) system is a
promising platform for nucleic acid detection. Regulating the CRISPR reaction would be …

CRISPR/Cas12, a highly efficient and specific nucleic acid recognition system, has been
broadly employed to detect amplified DNA products. However, most reported methods adopt …

The characteristic growth habit, abundant green foliage, and aromatic inflorescences of
cannabis provide the plant with an ideal profile as an ornamental plant. However, due to …

Salt stress affects large cultivated areas worldwide, thus causing remarkable reductions in
plant growth and yield. To reduce the negative effects of salt stress on plant growth and …