Calcitonin gene-related peptide (CGRP) antagonists are a class of medications that act as
antagonists of the CGRP receptor or ligand. They can be divided into monoclonal antibodies …

Calcitonin gene-related peptide (CGRP), a 37 amino-acid neuropeptide found mostly in
peptidergic sensory C-fibers, has been suggested to be implicated in the pathogenesis of …

Abstract Rimegepant [Nurtec® ODT (USA); Vydura®(EU)] is a calcitonin gene-related
peptide (CGRP) receptor antagonist approved for the acute treatment of migraine with or …

Targeting CGRP has proved to be efficacious, tolerable, and safe to treat migraine; however,
many patients with migraine do not benefit from drugs that antagonize the CGRPergic …

The main objective of this clinical practice guideline is to provide a series of
recommendations for healthcare and exercise professionals, such as neurologists, physical …

Calcitonin gene-related peptide (CGRP) is probably the most potent vasodilator in cerebral
circulation. Forty years after its discovery, the new CGRP-targeted therapy monoclonal …

Background In the absence of head-to-head trials, comprehensive evidence comparing
onset of efficacy of novel agents for acute treatment of migraine is lacking. This study aimed …

Chronic low back pain (CLBP) has been proved to be the dominating cause of disability in
patients with lumbar degenerative diseases. Of the various etiological factors, intervertebral …

Background: For many years triptans have been the cornerstone of acute migraine
treatment. Nevertheless, treatment with triptans may not always be initiated due to …

Background Neuroimaging studies have made an important contribution to our
understanding of headache pathophysiology. This systematic review aims to provide a …