Over the past decades, peroxisomes have emerged as key regulators in overall cellular lipid
and reactive oxygen species metabolism. In mammals, these organelles have also been …

Carnitine plays an essential role in mitochondrial fatty acid β-oxidation as a part of a cycle
that transfers long-chain fatty acids across the mitochondrial membrane and involves two …

The methylotrophic yeast Pichia pastoris is widely used in the manufacture of industrial
enzymes and pharmaceuticals. Like most biotechnological production hosts, P. pastoris is …

Long-chain fatty acid (LCFA) oxidation has been shown to play an important role in
interleukin-4 (IL-4)-mediated macrophage polarization (M (IL-4)). However, many of these …

In humans, peroxisomes harbor a complex set of enzymes acting on various lipophilic
carboxylic acids, organized in two basic pathways, α-oxidation and β-oxidation; the latter …

Peroxisomes are metabolic organelles involved in lipid metabolism and cellular redox
balance. Peroxisomal function is central to fatty acid oxidation, ether phospholipid synthesis …

Reduction-oxidation or “redox” reactions are an integral part of a broad range of cellular
processes such as gene expression, energy metabolism, protein import and folding, and …

Translational readthrough gives rise to low abundance proteins with C-terminal extensions
beyond the stop codon. To identify functional translational readthrough, we estimated the …

The cytochrome P450 gene 4 family (CYP4) consists of a group of over 63 members that ω-
hydroxylate the terminal carbon of fatty acids. In mammals, six subfamilies have been …

Membrane-bound organelles in eukaryotic cells form an interactive network to coordinate
and facilitate cellular functions. The formation of close contacts, termed “membrane contact …