Stemness in cancer: stem cells, cancer stem cells, and their microenvironment
Stemness combines the ability of a cell to perpetuate its lineage, to give rise to differentiated
cells, and to interact with its environment to maintain a balance between quiescence …
cells, and to interact with its environment to maintain a balance between quiescence …
Differences and similarities between cancer and somatic stem cells: therapeutic implications
F Rossi, H Noren, R Jove, V Beljanski… - Stem cell research & …, 2020 - Springer
Over the last decades, the cancer survival rate has increased due to personalized therapies,
the discovery of targeted therapeutics and novel biological agents, and the application of …
the discovery of targeted therapeutics and novel biological agents, and the application of …
The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer
S Melissaridou, E Wiechec, M Magan, MV Jain… - Cancer cell …, 2019 - Springer
Abstract Background Head and Neck Squamous Cell Carcinoma (HNSCC) tumors are often
resistant to therapies. Therefore searching for predictive markers and new targets for …
resistant to therapies. Therefore searching for predictive markers and new targets for …
[HTML][HTML] Lipid metabolism alteration contributes to and maintains the properties of cancer stem cells
Lipids, the basic components of the cell membrane, execute fundamental roles in almost all
the cell activities including cell-cell recognition, signalling transduction and energy supplies …
the cell activities including cell-cell recognition, signalling transduction and energy supplies …
Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer
Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …
Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer
Although blocking the binding of vascular endothelial growth factor (VEGF) to neuropilin-2
(NRP2) on tumor cells is a potential strategy to treat aggressive carcinomas, a lack of …
(NRP2) on tumor cells is a potential strategy to treat aggressive carcinomas, a lack of …
Focus on formononetin: anticancer potential and molecular targets
SKL Ong, MK Shanmugam, L Fan, SE Fraser, F Arfuso… - Cancers, 2019 - mdpi.com
Formononetin, an isoflavone, is extracted from various medicinal plants and herbs, including
the red clover (Trifolium pratense) and Chinese medicinal plant Astragalus membranaceus …
the red clover (Trifolium pratense) and Chinese medicinal plant Astragalus membranaceus …
CD44/CD44v6 a reliable companion in cancer-initiating cell maintenance and tumor progression
Z Wang, K Zhao, T Hackert, M Zöller - Frontiers in cell and …, 2018 - frontiersin.org
Metastasis is the leading cause of cancer death, tumor progression proceeding through
emigration from the primary tumor, gaining access to the circulation, leaving the circulation …
emigration from the primary tumor, gaining access to the circulation, leaving the circulation …
LncRNA SNHG5 promotes the proliferation and cancer stem cell-like properties of HCC by regulating UPF1 and Wnt-signaling pathway
Y Li, J Hu, D Guo, W Ma, X Zhang, Z Zhang, G Lu… - Cancer gene …, 2022 - nature.com
The role of long noncoding RNA (lncRNAs) had been demonstrated in different types of
cancer, including hepatocellular carcinoma. This study was intended to investigate the role …
cancer, including hepatocellular carcinoma. This study was intended to investigate the role …
EMT‐and MET‐related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities
The epithelial‐to mesenchymal (EMT) process is increasingly recognized for playing a key
role in the progression, dissemination, and therapy resistance of epithelial tumors …
role in the progression, dissemination, and therapy resistance of epithelial tumors …