Optical imaging modalities for biomedical applications

AP Dhawan, B D'Alessandro… - IEEE Reviews in …, 2010 - ieeexplore.ieee.org
Optical photographic imaging is a well known imaging method that has been successfully
translated into biomedical applications such as microscopy and endoscopy. Although …

Engineered multifunctional nanocarriers for cancer diagnosis and therapeutics

D Shi, NM Bedford, HS Cho - small, 2011 - Wiley Online Library
This article reviews advances in the design and development of multifunctional carbon‐
based and/or magnetic nanoparticle systems (or simply 'nanocarriers') for early cancer …

Direct approach to compute Jacobians for diffuse optical tomography using perturbation Monte Carlo-based photon “replay”

R Yao, X Intes, Q Fang - Biomedical optics express, 2018 - opg.optica.org
Perturbation Monte Carlo (pMC) has been previously proposed to rapidly recompute optical
measurements when small perturbations of optical properties are considered, but it was …

Quantum dots based molecular beacons for in vitro and in vivo detection of MMP-2 on tumor

X Li, D Deng, J Xue, L Qu, S Achilefu, Y Gu - Biosensors and Bioelectronics, 2014 - Elsevier
Abstract Matrix metalloproteinase-2 (MMP-2) is a protease related to tumor invasion and
metastasis. It is heavily secreted by malignant tumor cells, allowing the protease to serve as …

A review of image reconstruction algorithms for diffuse optical tomography

S Okawa, Y Hoshi - Applied Sciences, 2023 - mdpi.com
Diffuse optical tomography (DOT) is a biomedical imaging modality that can reconstruct
hemoglobin concentration and associated oxygen saturation by using detected light passing …

Transcranial photobiomodulation with near-infrared light from childhood to elderliness: simulation of dosimetry

Y Yuan, P Cassano, M Pias, Q Fang - Neurophotonics, 2020 - spiedigitallibrary.org
Significance: Major depressive disorder (MDD) affects over 40 million US adults in their
lifetime. Transcranial photobiomodulation (t-PBM) has been shown to be effective in treating …

Quantitative imaging of single upconversion nanoparticles in biological tissue

A Nadort, VKA Sreenivasan, Z Song, EA Grebenik… - PloS one, 2013 - journals.plos.org
The unique luminescent properties of new-generation synthetic nanomaterials,
upconversion nanoparticles (UCNPs), enabled high-contrast optical biomedical imaging by …

First clinical results of fluorescence lifetime-enhanced tumor imaging using receptor-targeted fluorescent probes

R Pal, ME Hom, NS van den Berg, TM Lwin… - Clinical Cancer …, 2022 - AACR
Purpose: Fluorescence molecular imaging, using cancer-targeted near infrared (NIR)
fluorescent probes, offers the promise of accurate tumor delineation during surgeries and …

Breast cancer: early-and late-fluorescence near-infrared imaging with indocyanine green—a preliminary study

A Poellinger, S Burock, D Grosenick, A Hagen… - Radiology, 2011 - pubs.rsna.org
Purpose To assess early-and late-fluorescence near-infrared imaging, corresponding to the
vascular (early-fluorescence) and extravascular (late-fluorescence) phases of indocyanine …

Hypoxia-targeting fluorescent nanobodies for optical molecular imaging of pre-invasive breast cancer

ASA van Brussel, A Adams, S Oliveira… - Molecular Imaging and …, 2016 - Springer
Purpose The aim of this work was to develop a CAIX-specific nanobody conjugated to
IRDye800CW for molecular imaging of pre-invasive breast cancer. Procedures CAIX …