[HTML][HTML] Synthesis and antimicrobial bioassays of 1, 3, 4-thiadiazole sulfone derivatives containing amide moiety: A study based on molecular dynamics (MD) …

L Yang, Q Liu, H Liu, D Chen, H Li, Z Chen… - Journal of Saudi Chemical …, 2022 - Elsevier
Abstract The backbone structure (1, 3, 4-thiadiazole sulfone derivatives containing amide
moiety) of target compounds was determined by modification and optimization of the …

Synthesis and antifungal activities of novel nicotinamide derivatives containing 1, 3, 4-oxadiazole

J Wu, S Kang, L Luo, Q Shi, J Ma, J Yin, B Song… - Chemistry Central …, 2013 - Springer
Background Pant diseases in agriculture are extremely difficult to control, which bring about
for billions of dollars in economic losses worldwide each year; Nicotinamide derivatives has …

Design, synthesis, and bioactivity evaluation of novel isoxazole-amide derivatives containing an acylhydrazone moiety as new active antiviral agents

ZB Yang, P Li, YJ He - Molecules, 2019 - mdpi.com
As a continuation of our efforts to discover and develop “me-better” active molecules, in this
study, a series of novel isoxazole-amide derivatives containing an acylhydrazone moiety …

Synthesis, Characterization, and Antifungal Activity of Novel Benzo[4,5]imidazo[1,2-d][1,2,4]triazine Derivatives

LX Li, J Jiao, XB Wang, M Chen, XC Fu, WJ Si… - Molecules, 2018 - mdpi.com
A series of novel fused heterocyclic compounds bearing benzo [4, 5] imidazo [1, 2-d][1, 2, 4]
triazine 4a–4w were designed and conveniently synthesized via the intermediates 2 …

Synthesis and biological evaluation of new Mannich and Schiff bases containing 1, 2, 4-triazole and 1, 3, 4-oxadiazole nucleus

S Ceylan - Medicinal Chemistry Research, 2016 - Springer
(Pyridine-3-yl)-1, 3, 4-oxadiazole-2-thiole 2, obtaining starting from nicotinic acid hydrazide
were converted to the corresponding Mannich bases (3a–c) by the reaction with several …

Target Discovery in Ralstonia solanacearum through an Activity-Based Protein Profiling Technique Based on Bioactive Oxadiazole Sulfones

B Chen, QS Long, J Meng, X Zhou, ZB Wu… - Journal of agricultural …, 2020 - ACS Publications
Ralstonia solanacearum is an extremely destructive and rebellious phytopathogen that can
cause bacterial wilt diseases in more than 200 plant species. To explore and discover the …

Pantoprazole derivatives: Synthesis, urease inhibition assay and in silico molecular modeling studies

H Azizian, A Esmailnejad, V Fathi Vavsari… - …, 2020 - Wiley Online Library
A number of pantoprazole derivatives were synthesized and screened for their urease
inhibitory properties. Some of them showed potent inhibitions against jack bean urease. All …

Novel Trifluoromethyl Pyridine Derivatives Bearing a 1, 3, 4‐Oxadiazole Moiety as Potential Insecticide

F Xu, Y Wang, D Luo, G Yu, Y Wu, A Dai… - …, 2018 - Wiley Online Library
A series of trifluoromethyl pyridine derivatives containing an 1, 3, 4‐oxadiazole moiety was
synthesized and characterized by 1H NMR, 19F NMR, 13C NMR, and HR‐MS. The bio …

Synthesis of oxadiazole-thiadiazole hybrids and their anticandidal activity

S Levent, B Kaya Çavuşoğlu, BN Sağlık, D Osmaniye… - Molecules, 2017 - mdpi.com
In the field of infection management, it is a major challenge to discover a potent and safe
antifungal agent due to the emergence of resistant strains. Hence, the goal of this paper is to …

Pyridine-Based Glycosides Bearing 1, 2, 4-Triazole and Their 1, 3, 4-oxadiazole analogues as Potential EGFR and CDK-2 Inhibitors: Design, Synthesis …

AF Kassem, A Younis, ES Nossier, HM Awad… - Journal of Molecular …, 2024 - Elsevier
The increasing toxicity of recently developed anticancer medications is seen as a serious
problem that stems from the variety of targets involved; as a result, more research on these …