Mitochondria are the energy center of the cell. They are found in the cell cytoplasm as
dynamic networks where they adapt energy production based on the cell's needs. They are …

Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

Gout is an autoinflammatory disease caused by the deposition of urate crystals. As the most
common inflammatory arthritis, gout has a high incidence and can induce various severe …

Inhaled allergens promote inflammatory response, tissue damage, and airway
hyperresponsiveness in the lungs, leading to allergic asthma. NLRP3, as an immune sensor …

Pharmacologically inhibiting nucleotide-binding domain and leucine-rich repeat-containing
(NLR) family, pyrin domain–containing protein 3 (NLRP3) inflammasome activation results …

Long‐term neurological deficits after severe traumatic brain injury (TBI), including cognitive
dysfunction and emotional impairments, can significantly impair rehabilitation. Glial …

Exposure to particulate matter (PM) 2.5 in air pollution is a serious health issue worldwide.
At present, effective prevention measures and modalities of treatment for PM2. 5-caused …

The NLRP3 inflammasome's core and most specific protein, NLRP3, has a variety of
functions in inflammation-driven diseases. Costunolide (COS) is the major active ingredient …

Background: One of the most common co-morbidities, that often leads to death, associated
with acute pancreatitis (AP) is represented by acute lung injury (ALI). While many aspects of …

Pain is a fundamental feature of inflammation. The immune system plays a critical role in the
activation of sensory neurons and there is increasing evidence of neuro-inflammatory …