Microdialysis of GABA and glutamate: analysis, interpretation and comparison with microsensors

M van der Zeyden, WH Oldenziel, K Rea… - Pharmacology …, 2008 - Elsevier
GABA and glutamate sampled from the brain by microdialysis do not always fulfill the classic
criteria for exocytotic release. In this regard the origin (neuronal vs. astroglial, synaptic vs …

Assaying protein unbound drugs using microdialysis techniques

TH Tsai - Journal of chromatography B, 2003 - Elsevier
Compared with traditional sampling methods, microdialysis is a technique for protein
unbound drug sampling without withdrawal of biological fluids and involving minimal …

In vivo monitoring of dopamine by microdialysis with 1 min temporal resolution using online capillary liquid chromatography with electrochemical detection

H Gu, EL Varner, SR Groskreutz, AC Michael… - Analytical …, 2015 - ACS Publications
Microdialysis is often applied to understanding brain function. Because neurotransmission
involves rapid events, increasing the temporal resolution of in vivo measurements is …

Microelectrode array studies of basal and potassium‐evoked release of l‐glutamate in the anesthetized rat brain

BK Day, F Pomerleau, JJ Burmeister… - Journal of …, 2006 - Wiley Online Library
Abstract l‐glutamate (Glu) is the predominant excitatory neurotransmitter in the mammalian
central nervous system. It plays major roles in normal neurophysiology and many brain …

Chronic second‐by‐second measures of l‐glutamate in the central nervous system of freely moving rats

EC Rutherford, F Pomerleau, P Huettl… - Journal of …, 2007 - Wiley Online Library
Abstract l‐glutamate (Glu) is the main excitatory neurotransmitter in the central nervous
system (CNS) and is associated with motor behavior and sensory perception. While …

Rapid microelectrode measurements and the origin and regulation of extracellular glutamate in rat prefrontal cortex

ER Hascup, KN Hascup, M Stephens… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 115, 1608–1620. Abstract Glutamate in the prefrontal cortex (PFC)
plays a significant role in several mental illnesses, including schizophrenia, addiction and …

Microfluidic electrophoresis chip coupled to microdialysis for in vivo monitoring of amino acid neurotransmitters

ZD Sandlin, M Shou, JG Shackman… - Analytical …, 2005 - ACS Publications
Microfluidic electrophoresis devices were coupled on-line to microdialysis for in vivo
monitoring of primary amine neurotransmitters in rat brain. The devices contained a sample …

Second-by-second measures of L-glutamate in the prefrontal cortex and striatum of freely moving mice

KN Hascup, ER Hascup, F Pomerleau, P Huettl… - … of Pharmacology and …, 2008 - ASPET
l-Glutamate (Glu) is the main excitatory neurotransmitter in the mammalian central nervous
system, and it is involved in most aspects of normal brain function, including cognition …

Time-resolved microdialysis for in vivo neurochemical measurements and other applications

KN Schultz, RT Kennedy - Annu. Rev. Anal. Chem., 2008 - annualreviews.org
Monitoring changes in chemical concentrations over time in complex environments is
typically performed using sensors and spectroscopic techniques. Another approach is to …

Quantitation of dopamine, serotonin and adenosine content in a tissue punch from a brain slice using capillary electrophoresis with fast-scan cyclic voltammetry …

H Fang, ML Pajski, AE Ross, BJ Venton - Analytical Methods, 2013 - pubs.rsc.org
Methods to determine neurochemical concentrations in small samples of tissue are needed
to map interactions among neurotransmitters. In particular, correlating physiological …