The emerging regulatory roles of non-coding RNAs associated with glucose metabolism in breast cancer
Altered energy metabolism is one of the hallmarks of tumorigenesis and essential for
fulfilling the high demand for metabolic energy in a tumor through accelerating glycolysis …
fulfilling the high demand for metabolic energy in a tumor through accelerating glycolysis …
Signaling circuitries in development: insights from the retinal determination gene network
SJ Silver, I Rebay - 2005 - journals.biologists.com
Context-specific integration of information received from the Notch, Transforming growth
factor β, Wingless/Wnt, Hedgehog and Epidermal growth factor receptor signaling pathways …
factor β, Wingless/Wnt, Hedgehog and Epidermal growth factor receptor signaling pathways …
[HTML][HTML] Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
K Bartscherer, N Pelte, D Ingelfinger, M Boutros - Cell, 2006 - cell.com
Wnt signaling pathways are important for multiple biological processes during development
and disease. Wnt proteins are secreted factors that activate target-gene expression in both a …
and disease. Wnt proteins are secreted factors that activate target-gene expression in both a …
Stem cells and retinal repair
Retinal stem cells (RSCs) are multipotent central nervous system (CNS) precursors that give
rise to the retina during the course of development. RSCs are present in the embryonic …
rise to the retina during the course of development. RSCs are present in the embryonic …
Wnt2b/β-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye
SH Cho, CL Cepko - 2006 - journals.biologists.com
Wnt signaling orchestrates multiple aspects of central nervous system development,
including cell proliferation and cell fate choices. In this study, we used gene transfer to …
including cell proliferation and cell fate choices. In this study, we used gene transfer to …
Coordinating proliferation and tissue specification to promote regional identity in the Drosophila head
KL Kenyon, SS Ranade, J Curtiss, M Mlodzik… - Developmental cell, 2003 - cell.com
Abstract The Decapentaplegic and Notch signaling pathways are thought to direct regional
specification in the Drosophila eye-antennal epithelium by controlling the expression of …
specification in the Drosophila eye-antennal epithelium by controlling the expression of …
The miR-30 family: Versatile players in breast cancer
SJ Yang, SY Yang, DD Wang, X Chen… - Tumor …, 2017 - journals.sagepub.com
The microRNA family, miR-30, plays diverse roles in regulating key aspects of neoplastic
transformation, metastasis, and clinical outcomes in different types of tumors. Accumulating …
transformation, metastasis, and clinical outcomes in different types of tumors. Accumulating …
[HTML][HTML] Ciliary margin transdifferentiation from neural retina is controlled by canonical Wnt signaling
H Liu, S Xu, Y Wang, C Mazerolle, S Thurig… - Developmental …, 2007 - Elsevier
The epithelial layers of the ciliary body (CB) and iris are non-neural structures that
differentiate from the anterior region of the eyecup, the ciliary margin (CM). We show here …
differentiate from the anterior region of the eyecup, the ciliary margin (CM). We show here …
Functional dissection of eyes absent reveals new modes of regulation within the retinal determination gene network
The retinal determination (RD) gene network encodes a group of transcription factors and
cofactors necessary for eye development. Transcriptional and posttranslational regulation of …
cofactors necessary for eye development. Transcriptional and posttranslational regulation of …
Condensin-mediated restriction of retrotransposable elements facilitates brain development in Drosophila melanogaster
BI Crawford, MJ Talley, J Russman, J Riddle… - Nature …, 2024 - nature.com
Neural stem and progenitor cell (NSPC) maintenance is essential for ensuring that
organisms are born with proper brain volumes and head sizes. Microcephaly is a disorder in …
organisms are born with proper brain volumes and head sizes. Microcephaly is a disorder in …