[HTML][HTML] Organ-on-a-chip: a survey of technical results and problems

AE Danku, EH Dulf, C Braicu, A Jurj… - … in bioengineering and …, 2022 - frontiersin.org
Organ-on-a-chip (OoC), also known as micro physiological systems or 'tissue chips' have
attracted substantial interest in recent years due to their numerous applications, especially in …

[HTML][HTML] Recent developments in microfluidic technology for synthesis and toxicity-efficiency studies of biomedical nanomaterials

A Bendre, MP Bhat, KH Lee, T Altalhi, MA Alruqi… - Materials Today …, 2022 - Elsevier
Microfluidic technology is a relatively new field among the various conventional bulk
techniques employed for nanomaterial synthesis. Nanoparticles (NPs) produced using such …

Advanced materials and sensors for microphysiological systems: focus on electronic and electrooptical interfaces

H Kavand, R Nasiri, A Herland - Advanced Materials, 2022 - Wiley Online Library
Advanced in vitro cell culture systems or microphysiological systems (MPSs), including
microfluidic organ‐on‐a‐chip (OoC), are breakthrough technologies in biomedicine. These …

[HTML][HTML] Emerging trends in organ-on-a-chip systems for drug screening

Y Wang, Y Gao, Y Pan, D Zhou, Y Liu, Y Yin… - … Pharmaceutica Sinica B, 2023 - Elsevier
New drug discovery is under growing pressure to satisfy the demand from a wide range of
domains, especially from the pharmaceutical industry and healthcare services. Assessment …

Organ-on-chip models for infectious disease research

R Alonso-Roman, AS Mosig, MT Figge… - Nature …, 2024 - nature.com
Research on microbial pathogens has traditionally relied on animal and cell culture models
to mimic infection processes in the host. Over recent years, developments in microfluidics …

State of the art in integrated biosensors for organ-on-a-chip applications

Y Zhu, K Mandal, AL Hernandez, S Kawakita… - Current Opinion in …, 2021 - Elsevier
Abstract Organ-on-a-chip (OoC) models are bioengineered tissue constructs integrated with
microfluidics that recapitulate the key features of the physiology of human organs and …

Organoid and microfluidics-based platforms for drug screening in COVID-19

R Ramezankhani, R Solhi, YC Chai, M Vosough… - Drug discovery today, 2022 - Elsevier
Highlights•Modelling platforms facilitate identification of therapeutic and prophylactic
approaches in COVID-19.•Genome based strategies and computational platforms have …

[HTML][HTML] Airway-on-a-chip: designs and applications for lung repair and disease

TJ Bennet, A Randhawa, J Hua, KC Cheung - Cells, 2021 - mdpi.com
The lungs are affected by illnesses including asthma, chronic obstructive pulmonary
disease, and infections such as influenza and SARS-CoV-2. Physiologically relevant models …

Recent advances of biosensor-integrated organ-on-a-chip technologies for diagnostics and therapeutics

A Shinde, K Illath, U Kasiviswanathan… - Analytical …, 2023 - ACS Publications
Conventional preclinical evaluation implemented in 2D monolayer cultures falls short with
multiorgan interactions, while animal systems lack the specificity of the human species …

[HTML][HTML] Microfluidic-Based Oxygen (O2) Sensors for On-Chip Monitoring of Cell, Tissue and Organ Metabolism

M Azimzadeh, P Khashayar, M Amereh, N Tasnim… - Biosensors, 2021 - mdpi.com
Oxygen (O2) quantification is essential for assessing cell metabolism, and its consumption in
cell culture is an important indicator of cell viability. Recent advances in microfluidics have …