[HTML][HTML] Role and recent advancements of ionic liquids in drug delivery systems

MK Shukla, H Tiwari, R Verma, WL Dong, S Azizov… - Pharmaceutics, 2023 - mdpi.com
Advancements in the fields of ionic liquids (ILs) broaden its applications not only in
traditional use but also in different pharmaceutical and biomedical fields. Ionic liquids …

Co-crystal nanoarchitectonics as an emerging strategy in attenuating cancer: Fundamentals and applications

P Kumbhar, K Kolekar, C Khot, S Dabhole… - Journal of Controlled …, 2023 - Elsevier
Cancer ranks as the second foremost cause of death in various corners of the globe. The
clinical uses of assorted anticancer therapeutics have been limited owing to the poor …

Two Novel Drug–Drug Cocrystals of Antifungal Clotrimazole with Nonsteroidal Anti-Inflammatory Drugs

KV Drozd, DE Boycov, AN Manin… - Crystal Growth & …, 2023 - ACS Publications
This work reports two novel drug–drug cocrystals of antifungal clotrimazole (CLT) with
nonsteroidal anti-inflammatory drugs, including niflumic acid (NFA) and diclofenac (DIC) …

[HTML][HTML] In Silico Screening as a Tool to Prepare Drug-Drug Cocrystals of Ibrutinib-Ketoconazole: a Strategy to Enhance Their Solubility Profiles and Oral …

DD Kara, PD Bangera, CH Mehta, K Tanvi… - AAPS …, 2023 - Springer
Ibrutinib (IBR) is a biopharmaceutical classification system (BCS) class II drug and an
irreversible Bruton's tyrosine kinase (BTK) inhibitor. IBR has an extremely low oral …

Crosslinked PVA-g-poly(AMPS) Nanogels for Enhanced Solubility and Dissolution of Ticagrelor: Synthesis, Characterization, and Toxicity Evaluation

U Saleem, I Khalid, L Hussain, A Alshammari… - ACS …, 2024 - ACS Publications
In this study, we synthesized PVA-g-poly (AMPS) nanogels with the aim of enhancing the
solubility and dissolution of ticagrelor (TGR). Ticagrelor, a noncompetitive, reversible P2Y12 …

Salts of Crizotinib with Dicarboxylic Acids: Structural Characteristic, Stability Analysis, and Solubility Performance

X Ou, C Liu, L Song, F Wu - Crystal Growth & Design, 2024 - ACS Publications
Crizotinib is a well-known anticancer medicine used for the targeted treatment of nonsmall
cell lung cancer. The water solubility of crizotinib is quite low and restricts its oral …

Advances in solvent based cocrystallization: Bridging the gap between theory and practice

S Sarangi, PN Remya, N Damodharan - Journal of Drug Delivery Science …, 2024 - Elsevier
A common tactic in materials science and pharmaceuticals is cocrystallization, which
synthesises multi-component crystalline materials with unique physicochemical …

Improving Dissolution Rate and Solubility of Palbociclib Salts/Cocrystal for Anticancer Efficacy

S Allu, JH An, BJ Park, WS Kim - Journal of Molecular Structure, 2024 - Elsevier
Palbociclib (PBC) is a highly effective drug for the treatment of breast cancer, but its full
potential is hindered by limited bioavailability due to poor water solubility and severe …

Elucidating of Fluconazole Cocrystallization With a Cutting-Edge Nutraceutical Coformer for Enhanced Formulation Strategies

P Vithlapara, M Chotaliya, D Mori, K Dudhat - Journal of Pharmaceutical …, 2024 - Springer
Introduction This current research reports the synthesis and characterization of a cocrystal of
Fluconazole (FLU), a widely used antifungal drug, with a nutraceutical coformer (NCF) that …

Exploring cocrystals of imatinib: synthesis, characterization, and in vitro evaluation

R Wadhwa, MRM Usman… - Journal of Survey in …, 2023 - sifisheriessciences.com
The limited efficacy of Imatinib as an anticancer agent is attributed to its significantly low
solubility and its bioavailability issues. To prepare the cocrystals of Imatinib (IMB) using a …