Gemtuzumab ozogamicin in combination with intensive chemotherapy in relapsed or refractory acute myeloid leukemia

SP Chantepie, E Reboursiere, JB Mear… - Leukemia & …, 2015 - Taylor & Francis
The prognosis of refractory/relapsed acute myeloid leukemia (AML) remains poor. The
complete response (CR) rate after relapse is around 25%, with 11% of patients still alive …

A galactosidase-responsive doxorubicin-folate conjugate for selective targeting of acute myelogenous leukemia blasts

J Clarhaut, S Fraineau, J Guilhot, E Peraudeau… - Leukemia Research, 2013 - Elsevier
Cytarabine combined with an anthracycline or an anthracenedione represents the usual
intensive induction therapy for the treatment of AML. However, this protocol induces severe …

MAC 作为55 岁以上急性髓系白血病患者挽救性治疗方案的疗效分析

赵邢力, 魏述宁, 刘凯奇, 林冬, 魏辉, 王迎, 周春林… - 中国实验血液学 …, 2015 - cqvip.com
目的: 评价MAC 方案作为老年急性髓系白血病(AML) 患者(≥ 55 岁) 挽救性治疗方案的疗效及
安全性. 方法: 收集33 例应用MAC 方案进行挽救性治疗的复发或诱导治疗未缓解的老年AML …

Fractionated doses of gemtuzumab ozogamicin combined with 3+ 7 induction chemotherapy as salvage treatment for young patients with acute myeloid leukemia in …

JV Malfuson, J Konopacki, C Thepenier, H Eddou… - Annals of …, 2012 - Springer
Current salvage therapies for relapsed acute myeloid leukemia (AML) are unsatisfactory. We
retrospectively evaluated the efficacy and toxicity of fractionated doses of gemtuzumab …

The addition of gemtuzumab ozogamicin to chemotherapy in adult patients with acute myeloid leukemia

J Kell - Expert Review of Anticancer Therapy, 2016 - Taylor & Francis
The treatment of acute myeloid leukaemia has remained largely unchanged for the last 30
years since the advent of combination chemotherapy with cytarabine arabinoside and …

Acute myeloid leukemia in the elderly (age 70 yr or older): long‐term survivors

M Heiblig, M Elhamri, C Le Jeune… - European Journal of …, 2017 - Wiley Online Library
Objective Little data exist regarding long‐term survival in elderly patients with acute myeloid
leukemia (AML). Methods In view of the fact that most deaths occurred during the first 3 yr …

New therapeutic strategies for high-risk acute myeloid leukemia

K Menghrajani, MS Tallman - Current opinion in hematology, 2018 - journals.lww.com
New therapeutic strategies for high-risk acute myeloid leuke... : Current Opinion in
Hematology New therapeutic strategies for high-risk acute myeloid leukemia : Current …

Antibody-based therapeutics targeting CD33, CD45, and CD66

RB Walter, OW Press, ID Bernstein - Targeted therapy of acute myeloid …, 2014 - Springer
Targeted therapy of acute myeloid leukemia (AML) with monoclonal antibodies (MoAbs) has
thus far been mostly directed at CD33, CD45, and CD66. The notion that some AMLs may …

Działania niepożądane przeciwciał monoklonalnych stosowanych w terapii nowotworów hematologicznych

M Maksymowicz, M Podhorecka - Varia Medica, 2022 - journals.viamedica.pl
Przeciwciała monoklonalne (mAb) podawane w monoterapii lub terapii skojarzonej
stanowią skuteczną opcję terapeutyczną w przypadku nowotworów hematologicznych …

Etude des altérations génomiques des leucémies aiguës myéloïdes de l'adulte: vers une approche thérapeutique personnalisée?

L Fenwarth - 2021 - theses.hal.science
Les leucémies aiguës myéloïdes (LAM) de l'adulte jeune représentent des entités
hétérogènes avec un pronostic contrasté. La classification pronostique de l'European …