Post-transcriptional regulation of cytokine and growth factor signaling in cancer
IVS Louis, PR Bohjanen - Cytokine & growth factor reviews, 2017 - Elsevier
Cytokines and growth factors regulate cell proliferation, differentiation, migration and
apoptosis, and play important roles in coordinating growth signal responses during …
apoptosis, and play important roles in coordinating growth signal responses during …
[HTML][HTML] HuR protein in hepatocellular carcinoma: implications in development, prognosis and treatment
V Papatheofani, G Levidou, P Sarantis, E Koustas… - Biomedicines, 2021 - mdpi.com
Hu-antigen R (HuR) is a post-transcriptional regulator that belongs to the embryonic lethal
abnormal vision Drosophila-like family (ELAV). HuR regulates the stability, translation …
abnormal vision Drosophila-like family (ELAV). HuR regulates the stability, translation …
[HTML][HTML] Discovery of the anti-angiogenesis effect of eltrombopag in breast cancer through targeting of HuR protein
Y Zhu, L Yang, J Xu, X Yang, P Luan, Q Cui… - … Pharmaceutica Sinica B, 2020 - Elsevier
HuR (human antigen R), an mRNA-binding protein responsible for poor prognosis in nearly
all kinds of malignancies, is a potential anti-tumor target for drug development. While …
all kinds of malignancies, is a potential anti-tumor target for drug development. While …
Potential mechanisms of microRNA mobility
H Lemcke, R David - Traffic, 2018 - Wiley Online Library
microRNAs (miRNAs) are important epigenetic modulators of gene expression that control
cellular physiology as well as tissue homeostasis, and development. In addition to the …
cellular physiology as well as tissue homeostasis, and development. In addition to the …
Relationship between HuR and tumor drug resistance
Q Ma, Q Lu, X Lei, J Zhao, W Sun, D Huang… - Clinical and …, 2023 - Springer
Human resistance protein R (HuR), also known as embryonic lethal abnormal visual-like
protein (ELAVL1), is an RNA-binding protein widely expressed in vivo that affects the mRNA …
protein (ELAVL1), is an RNA-binding protein widely expressed in vivo that affects the mRNA …
Role of post‐transcriptional regulation of mRNA stability in renal pathophysiology: focus on chronic kidney disease
E Feigerlovà, SF Battaglia‐Hsu - The FASEB Journal, 2017 - Wiley Online Library
Chronic kidney disease (CKD) represents an important public health problem. Its
progression to end‐stage renal disease is associated with increased morbidity and mortality …
progression to end‐stage renal disease is associated with increased morbidity and mortality …
Regulation of mRNA stability by RBPs and noncoding RNAs contributing to the pathogenicity of Th17 cells
Y Zhang, Z Wei, H Dong, J Zhou, J Yuan, B Ni, Y Wu… - RNA biology, 2021 - Taylor & Francis
Th17 cells remain one of the most important subsets of T cells in numerous autoimmune and
chronic inflammatory diseases. Posttranscriptional regulation (PTR), especially mRNA …
chronic inflammatory diseases. Posttranscriptional regulation (PTR), especially mRNA …
[HTML][HTML] RNA 结合蛋白ELAVL1 的功能及其调控病毒复制的研究进展
余祖华, 高梦茹, 齐志颖, 张静雨, 何雷, 陈建, 丁轲 - 畜牧兽医学报, 2024 - html.rhhz.net
胚胎致死异常视觉蛋白1 (embryonic lethal abnormal vision like 1, ELAVL1),
又被称为人类抗原R (human antigen R, HuR), 是一种典型的RNA 结合蛋白(RNA binding …
又被称为人类抗原R (human antigen R, HuR), 是一种典型的RNA 结合蛋白(RNA binding …
RNA-binding protein HuR enhances mineralocorticoid signaling in renal KC3AC1 cells under hypotonicity
I Lema, L Amazit, K Lamribet, J Fagart… - Cellular and Molecular …, 2017 - Springer
Mineralocorticoid receptor (MR) mediates the sodium-retaining action of aldosterone in the
distal nephron. Herein, we decipher mechanisms by which hypotonicity increases MR …
distal nephron. Herein, we decipher mechanisms by which hypotonicity increases MR …
[HTML][HTML] Advantages of using paclitaxel in combination with oncolytic adenovirus utilizing RNA destabilization mechanism
Oncolytic virotherapy is a novel approach to cancer therapy. Ad-fos ARE is a conditionally
replicative adenovirus engineered by inserting AU-rich elements (ARE) in the 3' …
replicative adenovirus engineered by inserting AU-rich elements (ARE) in the 3' …