[HTML][HTML] Cerebral small vessel disease alters neurovascular unit regulation of microcirculation integrity involved in vascular cognitive impairment

Q Yang, X Wei, B Deng, Z Chang, D Jin, Y Huang… - Neurobiology of …, 2022 - Elsevier
Cerebral small vessel disease (CSVD) is a generic term used for intracranial vascular
disorders caused by the structural changes of cerebral microvessels, including the small …

[HTML][HTML] Cell non-autonomous regulation of cerebrovascular aging processes by the somatotropic axis

MA Bickel, B Csik, R Gulej, A Ungvari… - Frontiers in …, 2023 - frontiersin.org
Age-related cerebrovascular pathologies, ranging from cerebromicrovascular functional and
structural alterations to large vessel atherosclerosis, promote the genesis of vascular …

[HTML][HTML] Increased extracellular fluid is associated with white matter fiber degeneration in CADASIL: in vivo evidence from diffusion magnetic resonance imaging

X Yu, X Yin, H Hong, S Wang, Y Jiaerken… - Fluids and Barriers of …, 2021 - Springer
Abstract Background White matter hyperintensities (WMHs) are one of the hallmarks of
cerebral small vessel disease (CSVD), but the pathological mechanisms underlying WMHs …

Emerging role of white matter lesions in cerebrovascular disease

A Rastogi, R Weissert… - European Journal of …, 2021 - Wiley Online Library
White matter lesions have been implicated in the setting of stroke, dementia, intracerebral
haemorrhage, several other cerebrovascular conditions, migraine, various …

Impaired dynamic cerebral autoregulation is associated with the severity of neuroimaging features of cerebral small vessel disease

Z Liu, H Ma, ZN Guo, L Wang, Y Qu… - CNS neuroscience & …, 2022 - Wiley Online Library
Aims Cerebral small vessel disease (CSVD) is characterized by functional and structural
changes in small vessels. We aimed to elucidate the relationship between dynamic cerebral …

Deep medullary veins are associated with widespread brain structural abnormalities

ZY Liu, FF Zhai, DH Ao, F Han, ML Li… - Journal of Cerebral …, 2022 - journals.sagepub.com
Our aim is to investigate the association of cerebral deep medullary veins (DMVs) with white
matter microstructural integrity and regional brain atrophy in MRI. In a community-based …

[HTML][HTML] Decreased cerebral blood flow and delayed arterial transit are independently associated with white matter hyperintensity

R Zhang, P Huang, S Wang, Y Jiaerken… - Frontiers in Aging …, 2022 - frontiersin.org
Aim-White matter hyperintensities (WMH) and lacunes were important features of cerebral
small vessel disease (CSVD), which contributes to 25% of ischemic strokes and 45% of …

Visualizing Cerebral Small Vessel Degeneration During Aging and Diseases Using Magnetic Resonance Imaging

P Huang, K Chen, C Liu, Z Zhen… - Journal of Magnetic …, 2023 - Wiley Online Library
Cerebral small vessel disease is a major contributor to brain disorders in older adults. It is
associated with a much higher risk of stroke and dementia. Due to a lack of clinical and fluid …

[HTML][HTML] White matter free water is a composite marker of cerebral small vessel degeneration

P Huang, R Zhang, Y Jiaerken, S Wang… - Translational stroke …, 2022 - Springer
To investigate the association between white matter free water (FW) and common imaging
markers of cerebral small vessel diseases (CSVD) in two groups of subjects with different …

Global changes in diffusion tensor imaging during acute ischemic stroke and post-stroke cognitive performance

KC Kern, CB Wright, R Leigh - Journal of Cerebral Blood …, 2022 - journals.sagepub.com
Post-stroke cognitive impairment is related to the effects of the acute stroke and pre-stroke
brain health. We tested whether diffusion tensor imaging (DTI) can detect acute, global …