White matter free water is a composite marker of cerebral small vessel degeneration

P Huang, R Zhang, Y Jiaerken, S Wang… - Translational stroke …, 2021 - Springer
To investigate the association between white matter free water (FW) and common imaging
markers of cerebral small vessel diseases (CSVD) in two groups of subjects with different …

Risk factors of impaired employability after cerebral venous thrombosis

L Liu, H Jiang, H Wei, Y Zhou, Y Wu… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims Cerebral venous thrombosis (CVT) is a major cause of stroke in young and middle‐
aged adults. This study aimed to evaluate the prevalence of post‐CVT employability decline …

Global changes in diffusion tensor imaging during acute ischemic stroke and post-stroke cognitive performance

KC Kern, CB Wright, R Leigh - Journal of Cerebral Blood …, 2022 - journals.sagepub.com
Post-stroke cognitive impairment is related to the effects of the acute stroke and pre-stroke
brain health. We tested whether diffusion tensor imaging (DTI) can detect acute, global …

Visualizing Cerebral Small Vessel Degeneration During Aging and Diseases Using Magnetic Resonance Imaging

P Huang, K Chen, C Liu, Z Zhen… - Journal of Magnetic …, 2023 - Wiley Online Library
Cerebral small vessel disease is a major contributor to brain disorders in older adults. It is
associated with a much higher risk of stroke and dementia. Due to a lack of clinical and fluid …

A novel severe cerebral venous thrombosis rat model based on semi‐ligation combined with ferric chloride and thrombin

L Xiao, X Ji, H Zhao, Y Luo, S Hu… - CNS neuroscience & …, 2022 - Wiley Online Library
Aims An applicable cerebral venous sinus thrombosis (CVST) model is imperative for
exploring its pathophysiology. We established a novel severe CVST model using semi …

Diffusion tensor free water MRI predicts progression of FLAIR white matter hyperintensities after ischemic stroke

KC Kern, MS Zagzoug, RF Gottesman… - Frontiers in …, 2023 - frontiersin.org
Background The progression of FLAIR white matter hyperintensities (WMHs) on MRI heralds
vascular-mediated cognitive decline. Even before FLAIR WMH progression, adjacent normal …

Sam50 exerts neuroprotection by maintaining the mitochondrial structure during experimental cerebral ischemia/reperfusion injury in rats

X Yin, J Wang, S Yang, H Li, H Shen… - CNS Neuroscience …, 2022 - Wiley Online Library
Aim To investigate the role of Sam50, a barrel protein on the surface of the mitochondrial
outer membrane, in cerebral ischemia–reperfusion (I/R) injury and its underlying …

Superficial white matter microstructure affects processing speed in cerebral small vessel disease

S Wang, F Zhang, P Huang, H Hong… - Human Brain …, 2022 - Wiley Online Library
White matter hyperintensities (WMH) are a typical feature of cerebral small vessel disease
(CSVD), which contributes to about 50% of dementias worldwide. Microstructural alterations …

[HTML][HTML] Association of deep medullary veins with the neuroimaging burden of cerebral small vessel disease

X Yin, Y Han, X Cao, Y Zeng, Y Tang… - … Imaging in Medicine …, 2023 - ncbi.nlm.nih.gov
Background This study aimed to explore the association between deep medullary veins
(DMVs) and the neuroimaging burden of cerebral small vessel disease (CSVD). Methods In …

Inferior Frontal Sulcal Hyperintensity on FLAIR Is Associated with Small Vessel Disease but not Alzheimer's Pathology

S Xu, L Xie, Y Zhang, X Wu, H Hong… - Journal of …, 2023 - content.iospress.com
Background: The inferior frontal sulci are essential sites on the route of cerebrospinal fluid
outflow. A recent study suggests that inferior frontal sulcal hyperintensities (IFSH) on FLAIR …