ABSTRACT QPX7728 is an ultrabroad-spectrum beta-lactamase inhibitor with potent
inhibition of key serine and metallo beta-lactamases. QPX7728 enhances the potency of …

(1) Background: The purpose of the study was to describe the activity of mex efflux pumps in
Multidrug-Resistant (MDR) clinical isolates of Pseudomonas aeruginosa and to compare the …

Ciprofloxacin is one of the most widely used antibiotics for treating Pseudomonas
aeruginosa infections. However, P. aeruginosa acquires mutations that confer ciprofloxacin …

The evolution of antimicrobial-resistant Gram-negative pathogens is a substantial menace to
public health sectors, notably in developing countries because of the scarcity of healthcare …

Antimicrobial resistance (AMR) is an escalating issue that can render illnesses more difficult
to treat if effective antibiotics become resistant. Many studies have explored antibiotic …

Klebsiella pneumoniae (K. pneumoniae) is involved in several hospital and community-
acquired infections. The prevalence of K. pneumoniae-producing-carbapenemase (KPC) …

Cefiderocol, a recently introduced antibiotic, has a chemical structure that includes a
cephalosporin that targets cell wall synthesis and a chlorocatechol siderophore moiety that …

The ability of Pseudomonas species to thrive in all major natural environments (ie terrestrial,
freshwater and marine) is based on its exceptional capability to adapt to physicochemical …

The manuscripts contained in this special edition of Antibiotics represent a current review of
the polymyxins as well as highlights from the 3rd International Polymyxin Conference, which …

In response to the pressing demand for functional nanomaterials synthesis and applications,
two polyelectrolyte complexes (PECs)[electrostatic and cross-linked nanogels (NGs)] loaded …