Reduced energy metabolism contributing to aging of skeletal muscle by serum metabolomics and gut microbiota analysis

P He, G Du, X Qin, Z Li - Life Sciences, 2023 - Elsevier
Aims Sarcopenia is an age-related syndrome characterized by a gradual loss of the muscle
mass, strength, and function. It is associated with a high risk of adverse consequences such …

A long-term obesogenic high-fat diet in mice partially dampens the anti-frailty benefits of late-life intermittent fasting

YO Henderson, N Bithi, J Yang, C Link, A Zhang… - Geroscience, 2023 - Springer
The global obesity pandemic coupled with ever-growing life expectancies equates to
hundreds of millions of individuals with potentially longer but not healthier lives. Aging is one …

Modeling functional limitations, gait impairments, and muscle pathology in alzheimer's disease: Studies in the 3xtg-ad mice

L Castillo-Mariqueo, MJ Pérez-García, L Giménez-Llort - Biomedicines, 2021 - mdpi.com
Gait impairments in Alzheimer's disease (AD) result from structural and functional
deficiencies that generate limitations in the performance of activities and restrictions in …

Zebrafish models for skeletal muscle senescence: lessons from cell cultures and rodent models

S Ichii, I Matsuoka, F Okazaki, Y Shimada - Molecules, 2022 - mdpi.com
Human life expectancy has markedly increased over the past hundred years. Consequently,
the percentage of elderly people is increasing. Aging and sarcopenic changes in skeletal …

Structure-Function relationships in the skeletal muscle extracellular matrix

RL Lieber, G Meyer - Journal of biomechanics, 2023 - Elsevier
The vast majority of skeletal muscle biomechanical studies have rightly focused on its active
contractile properties. However, skeletal muscle passive biomechanical properties have …

CircTmeff1 Promotes Muscle Atrophy by Interacting with TDP‐43 and Encoding A Novel TMEFF1‐339aa Protein

R Chen, T Yang, B Jin, W Xu, Y Yan, N Wood… - Advanced …, 2023 - Wiley Online Library
Skeletal muscle atrophy is a common clinical feature of many acute and chronic conditions.
Circular RNAs (circRNAs) are covalently closed RNA transcripts that are involved in various …

Photobiomodulation therapy on skeletal muscles exposed to diabetes mellitus: a systematic review of animal studies

F dos Santos Soares, M de Souza Pinto… - Lasers in Medical …, 2023 - Springer
Diabetes-related muscle damage has been overlooked despite its known association with
increased morbidity and mortality in DM individuals. PBMT is a recognized alternative to …

[HTML][HTML] Astragulus embranaceus (Fisch.) Bge-Dioscorea opposita Thunb herb pair ameliorates sarcopenia in senile type 2 diabetes mellitus through Rab5a/mTOR …

M She, M Huang, J Zhang, Y Yan, L Zhou… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance The combination of Astragulus embranaceus (Fisch.) Bge
(Huangqi) and Dioscorea opposita Thunb (Shanyao) are one of the most widely accepted …

[HTML][HTML] Advances in research on cell models for skeletal muscle atrophy

L Li, C Huang, J Pang, Y Huang, X Chen… - Biomedicine & …, 2023 - Elsevier
Skeletal muscle, the largest organ in the human body, plays a crucial role in supporting and
defending the body and is essential for movement. It also participates in regulating the …

Novel Insights Into the Multifaceted Functions of RNA n6-Methyladenosine Modification in Degenerative Musculoskeletal Diseases

H Li, WF Xiao, Y He, Z Wen, S Cheng… - Frontiers in cell and …, 2021 - frontiersin.org
N6-methyladenosine (m6A) is an important modification of eukaryotic mRNA. Since the first
discovery of the corresponding demethylase and the subsequent identification of m6A as a …