[HTML][HTML] Recent advances in nanoparticle-based Co-delivery systems for cancer therapy

RD Al Bostami, WH Abuwatfa, GA Husseini - Nanomaterials, 2022 - mdpi.com
Cancer therapies have advanced tremendously throughout the last decade, yet multiple
factors still hinder the success of the different cancer therapeutics. The traditional therapeutic …

Immune exosomes loading self-assembled nanomicelles traverse the blood–brain barrier for chemo-immunotherapy against glioblastoma

J Cui, X Wang, J Li, A Zhu, Y Du, W Zeng, Y Guo, L Di… - ACS …, 2023 - ACS Publications
Effective drug delivery and prevention of postoperative recurrence are significant challenges
for current glioblastoma (GBM) treatment. Poor drug delivery is mainly due to the presence …

[HTML][HTML] Cancer cell-mitochondria hybrid membrane coated Gboxin loaded nanomedicines for glioblastoma treatment

Y Zou, Y Sun, Y Wang, D Zhang, H Yang… - Nature …, 2023 - nature.com
Glioblastoma (GBM) remains the most lethal malignant tumours. Gboxin, an oxidative
phosphorylation inhibitor, specifically restrains GBM growth by inhibiting the activity of F0F1 …

Metal-organic framework nanoagent induces cuproptosis for effective immunotherapy of malignant glioblastoma

QX Huang, JL Liang, QW Chen, XK Jin, MT Niu… - Nano Today, 2023 - Elsevier
Glioblastoma (GBM) is an aggressive brain cancer with an immunosuppressive tumor
microenvironment. Here, a copper-based nanoplatform BSO-CAT@ MOF-199@ DDM …

Engineering nanosystems for ROS-bridged cancer cascade therapy

Q Fu, L Yu, M Zhang, S Li, L Liu - Chemical Engineering Journal, 2023 - Elsevier
Developing efficient cancer treatment modalities is crucial, given the tens of thousands of
deaths that cancer causes each year. Although there are various treatment modalities …

Biomimetic nanosonosensitizers combined with noninvasive ultrasound actuation to reverse drug resistance and sonodynamic-enhanced chemotherapy against …

H Chen, S Zhang, Q Fang, H He, J Ren, D Sun, J Lai… - ACS …, 2022 - ACS Publications
Glioblastoma (GBM) is the most devastating brain tumor and highly resistant to conventional
chemotherapy. Herein, we introduce biomimetic nanosonosensitizer systems (MDNPs) …

An Activatable Prodrug Nanosystem for Ultrasound‐Driven Multimodal Tumor Therapy and Metastasis Inhibition

J Zheng, H Ge, D Zhou, Q Yao, S Long… - Advanced …, 2023 - Wiley Online Library
Ultrasound, featuring deep tissue penetration and noninvasiveness, offers a new opportunity
to activate functional materials in a tumor‐selective manner. However, very few direct …

A supramolecular assembly strategy for hydrophilic drug delivery towards synergistic cancer treatment

H Qu, H Chen, W Cheng, Y Wang, Y Xia, L Zhang… - Acta Biomaterialia, 2023 - Elsevier
To improve the drug loading, tumor targeting, and delivery simplicity of hydrophilic drugs, we
propose a supramolecular assembly strategy that potentially benefits a wide range of …

Fruit‐Derived Extracellular‐Vesicle‐Engineered Structural Droplet Drugs for Enhanced Glioblastoma Chemotherapy

J Chen, J Pan, S Liu, Y Zhang, S Sha, H Guo… - Advanced …, 2023 - Wiley Online Library
Existing solid‐nanoparticle‐based drug delivery systems remain a great challenge for
glioblastoma chemotherapy due to their poor capacities in crossing the blood–brain …

Homotypic membrane-enhanced blood–brain barrier crossing and glioblastoma targeting for precise surgical resection and photothermal therapy

H Zhang, S Guan, T Wei, T Wang, J Zhang… - Journal of the …, 2023 - ACS Publications
The crossing of blood–brain barrier (BBB) is essential for glioblastoma (GBM) therapy, and
homotypic targeting is an effective strategy to achieve BBB crossing. In this work, GBM …