Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by
gradual loss of memory and cognitive function, which constitutes a heavy burden on the …

Forkhead box O (FOXO) transcription factors regulate diverse biological processes, affecting
development, metabolism, stem cell maintenance and longevity. They have also been …

TIA-1 is an RNA binding protein that promotes the assembly of stress granules (SGs),
discrete cytoplasmic inclusions into which stalled translation initiation complexes are …

Abstract Purpose of Review This review summarizes the alterations in the β-cell observed in
type 2 diabetes (T2D), focusing on changes in β-cell identity and mass and changes …

Hypoxia is a dynamic feature of the tumor microenvironment that contributes to cancer
progression. In order to adapt and overcome hypoxic stress, tumor cells activate survival …

Pathological increases in cell death in the liver as well as in peripheral tissues has emerged
as an important mechanism involved in the development and progression of nonalcoholic …

The distal hereditary motor neuropathies (dHMN) comprise a heterogenous group of
diseases that share the common feature of a length-dependent predominantly motor …

Immunogenic cell death (ICD) offers a method of stimulating the immune system to attack
and remove cancer cells. We report a copper (II) complex containing a Schiff base ligand …

Chikungunya virus (CHIKV) is an arthropod-borne virus (arbovirus) of epidemic concern,
transmitted by Aedes ssp. mosquitoes, and is the etiologic agent of a febrile and …

Individuals with Parkinson's disease (PD) experience a progressive decline in motor
function as a result of selective loss of dopaminergic (DA) neurons in the substantia nigra …