We present in vivo measurements of baseline physiology from five subjects with a four-
wavelength (690, 750, 800, and 850 nm) time-resolved optical system. The measurements …

We present a deep learning framework for wide-field, content-aware estimation of
absorption and scattering coefficients of tissues, called Generative Adversarial Network …

The fluorescence spectrum measured from a fluorophore in tissue is affected by the
absorption and scattering properties of the tissue, as well as by the measurement geometry …

A mechanically switchable solid inhomogeneous phantom simulating localized absorption
changes was developed and characterized. The homogeneous host phantom was made of …

Significance Interstitial fiber-based spectroscopy is gaining interest for real-time in vivo
optical biopsies, endoscopic interventions, and local monitoring of therapy. Different from …

We present a new method for the accurate estimation of diffuse reflectance spectra from
RGB values based on Wiener estimation. In the proposed method, a system matrix obtained …

Near-infrared (NIR) spectroscopy is a useful technique for quantitative measurements of
intact tablets, but it suffers from limitations due to the fact that changes in the physical …

We describe a compact fiber-optic probe (2 mm outside diameter) that utilizes spatially-
resolved diffuse reflectance for tissue optical property recovery. Validation was performed in …

The number of near-infrared (NIR) spectroscopic applications in the pharmaceutical
sciences has grown significantly in the last decade. Despite its widespread application, the …

Functional near-infrared spectroscopy (fNIRS) is a non-invasive and promising method for
continuously monitoring hemodynamic and metabolic changes in tissues. However, the …