The inhibitory effects of pentacyclic triterpenes from loquat leaf against Th17 differentiation
X Zhou, H Chen, F Wei, Q Zhao, Q Su… - Immunological …, 2020 - Taylor & Francis
Background Loquat leaf is an herb that is commonly used in traditional Chinese medicine
(TCM) for its anti-inflammatory properties. Numerous studies have demonstrated that Th17 …
(TCM) for its anti-inflammatory properties. Numerous studies have demonstrated that Th17 …
The role of Nrf2 in autoimmunity and infectious disease: Therapeutic possibilities
RA Freeborn, CE Rockwell - Advances in Pharmacology, 2021 - Elsevier
Nrf2 is a cytoprotective transcription factor which is involved in ameliorating oxidative stress
and toxic insults. Recently, an immunomodulatory role for Nrf2 has gained appreciation as it …
and toxic insults. Recently, an immunomodulatory role for Nrf2 has gained appreciation as it …
Altered redox regulation by Nrf2-Keap1 system in dendritic cells of systemic lupus erythematosus patients
P Gautam, G Kaur, A Tandon, A Sharma… - Lupus, 2020 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is an autoimmune disorder associated with
inflammation and multiple organ involvement. Individually, dendritic cells (DCs) and …
inflammation and multiple organ involvement. Individually, dendritic cells (DCs) and …
Proximal and distal regions of pathogenic th17 related chromatin loci are sequentially accessible during pathogenicity of th17
L Hu, X Zhao, P Li, Y Zeng, Y Zhang, Y Shen… - Frontiers in …, 2022 - frontiersin.org
Pathogenic Th17, featured by their production of pro-inflammatory cytokines, are considered
as a key player in most autoimmune diseases. The transcriptome of them is obviously …
as a key player in most autoimmune diseases. The transcriptome of them is obviously …
3β‐Acetyloxy‐oleanolic Acid Attenuates Pristane‐Induced Lupus Nephritis by Regulating Th17 Differentiation
X Zhou, H Chen, F Wei, Q Zhao, Q Su… - Journal of …, 2019 - Wiley Online Library
Th17 activity has been implicated in systemic lupus erythematosus (SLE), which is a
systemic autoimmune disease with a typical clinical manifestation of lupus nephritis (LN) …
systemic autoimmune disease with a typical clinical manifestation of lupus nephritis (LN) …
Th17 cells: A new target in kidney disease research
T Zhang, H Huo, Y Zhang, J Tao, J Yang… - International Reviews …, 2024 - Taylor & Francis
Abstract Type 17 T helper (Th17) cells, which are a subtype of CD4+ T helper cells, secrete
pro-inflammatory cytokines such as IL-17A, IL-17F, IL-21, IL-22, and GM-CSF, which play …
pro-inflammatory cytokines such as IL-17A, IL-17F, IL-21, IL-22, and GM-CSF, which play …
Focusing on T-Cells for Novel Treatments of Systemic Lupus Erythematosus
K Ichinose, CM Hedrich, VR Moulton… - Frontiers in …, 2021 - frontiersin.org
The pathogenesis of Systemic Lupus Erythematosus (SLE) involves all components of the
immune system, including immune cells (T cells, B cells, antigen presenting cells) …
immune system, including immune cells (T cells, B cells, antigen presenting cells) …
Puberty exposure to cigarette smoke extract impairs adult spermatogenesis in the mouse
G Zhao, J Mo, T Zheng, Y Li, X Wu, J Huang, G Liu… - Reproductive …, 2019 - Elsevier
Epidemiological studies suggested that exposure to cigarette smoke early in life is
associated with long-term health risks. Using a nuclear factor erythroid 2-related factor 2 …
associated with long-term health risks. Using a nuclear factor erythroid 2-related factor 2 …
Nrf2 in Immune Responses During Inflammation
One of the most studied functions of Nrf2 is its role in the maintenance of redox homeostasis
in cells during oxidant stress. However, the role of Nrf2 in tissue and organism homoeostasis …
in cells during oxidant stress. However, the role of Nrf2 in tissue and organism homoeostasis …