Betulinic acid regulates tumor-associated macrophage M2 polarization and plays a role in inhibiting the liver cancer progression

L Guo, H Pei, Y Yang, Y Kong - International Immunopharmacology, 2023 - Elsevier
Objective To investigate the regulatory role and mechanism of betulinic acid (BET) in tumor-
associated M2 macrophage polarization. Methods For in vitro experiments, RAW246. 7 and …

Etrinabdione (VCE-004.8), a B55α activator, promotes angiogenesis and arteriogenesis in critical limb ischemia

A Garcia-Martin, ME Prados, I Lastres-Cubillo… - bioRxiv, 2024 - biorxiv.org
Background Vasculogenic therapies explored for the treatment of peripheral artery disease
(PAD) have encountered minimal success in clinical trials. Addressing this, B55α, an isoform …