Self-assembly of organic nanomaterials and biomaterials: The bottom-up approach for functional nanostructures formation and advanced applications

D Lombardo, P Calandra, L Pasqua, S Magazù - Materials, 2020 - mdpi.com
In this paper, we survey recent advances in the self-assembly processes of novel functional
platforms for nanomaterials and biomaterials applications. We provide an organized …

[HTML][HTML] Ultrashort peptide self-assembly: front-runners to transport drug and gene cargos

S Gupta, I Singh, AK Sharma, P Kumar - Frontiers in bioengineering …, 2020 - frontiersin.org
The translational therapies to promote interaction between cell and signal come with
stringent eligibility criteria. The chemically defined, hierarchically organized, and simpler yet …

Biomaterial‐based gene therapy

Y Yu, Y Gao, L He, B Fang, W Ge, P Yang, Y Ju… - MedComm, 2023 - Wiley Online Library
Gene therapy, a medical approach that involves the correction or replacement of defective
and abnormal genes, plays an essential role in the treatment of complex and refractory …

Peptide-based nanoparticles for therapeutic nucleic acid delivery

P Boisguérin, K Konate, E Josse, E Vivès, S Deshayes - Biomedicines, 2021 - mdpi.com
Gene therapy offers the possibility to skip, repair, or silence faulty genes or to stimulate the
immune system to fight against disease by delivering therapeutic nucleic acids (NAs) to a …

Oncogenic properties of the EBV ZEBRA protein

D Germini, FB Sall, A Shmakova, J Wiels… - Cancers, 2020 - mdpi.com
Epstein Barr Virus (EBV) is one of the most common human herpesviruses. After primary
infection, it can persist in the host throughout their lifetime in a latent form, from which it can …

Materials promoting viral gene delivery

K Kaygisiz, CV Synatschke - Biomaterials Science, 2020 - pubs.rsc.org
Therapeutic viral gene delivery is an emerging technology which aims to correct genetic
mutations by introducing new genetic information to cells either to correct a faulty gene or to …

Recent progress in nanomedicine-mediated cytosolic delivery

H Son, J Shin, J Park - RSC advances, 2023 - pubs.rsc.org
Cytosolic delivery of bioactive agents has exhibited great potential to cure undruggable
targets and diseases. Because biological cell membranes are a natural barrier for living …

Bacteriophage P22 capsid as a pluripotent nanotechnology tool

VA Essus, GS Souza Júnior, GHP Nunes, JS Oliveira… - Viruses, 2023 - mdpi.com
The Salmonella enterica bacteriophage P22 is one of the most promising models for the
development of virus-like particle (VLP) nanocages. It possesses an icosahedral T= 7 …

Virus-inspired strategies for cancer therapy

XY Ma, BD Hill, T Hoang, F Wen - Seminars in cancer biology, 2022 - Elsevier
The intentional use of viruses for cancer therapy dates back over a century. As viruses are
inherently immunogenic and naturally optimized delivery vehicles, repurposing viruses for …

[HTML][HTML] Approaches for evaluation of novel CPP-based cargo delivery systems

L Porosk, Ü Langel - Frontiers in Pharmacology, 2022 - frontiersin.org
Cell penetrating peptides (CPPs) can be broadly defined as relatively short synthetic, protein
derived or chimeric peptides. Their most remarkable property is their ability to cross cell …