Iron supplementation enhances RSL3-induced ferroptosis to treat naïve and prevent castration-resistant prostate cancer
F Maccarinelli, D Coltrini, S Mussi, M Bugatti… - Cell Death …, 2023 - nature.com
Prostate cancer (PCa) is a leading cause of death in the male population commonly treated
with androgen deprivation therapy that often relapses as androgen-independent and …
with androgen deprivation therapy that often relapses as androgen-independent and …
Analysis of genetic biomarkers, polymorphisms in ADME-related genes and their impact on pharmacotherapy for prostate cancer
K Rehman, Z Iqbal, D Zhiqin, H Ayub, N Saba… - Cancer Cell …, 2023 - Springer
Prostate cancer (PCa) is a non-cutaneous malignancy in males with wide variation in
incidence rates across the globe. It is the second most reported cause of cancer death. Its …
incidence rates across the globe. It is the second most reported cause of cancer death. Its …
A novel intronic circular RNA circFGFR1int2 up-regulates FGFR1 by recruiting transcriptional activators P65/FUS and suppressing miR-4687-5p to promote prostate …
R Wang, J Zhong, X Pan, Z Su, Y Xu, M Zhang… - Journal of Translational …, 2023 - Springer
Fibroblast growth factor receptor 1 (FGFR1) is a core component of the FGFs/FGFR pathway
that activates multiple signalling pathways, including ERK1/2, PI3K/AKT, PLCγ, and NF-κB …
that activates multiple signalling pathways, including ERK1/2, PI3K/AKT, PLCγ, and NF-κB …
Humanized disulfide‐stabilized diabody against fibroblast growth factor‐2 inhibits PD‐L1 expression and epithelial‐mesenchymal transition in hepatoma cells through …
H Sun, X Song, C Li, Q Li, S Liu, N Deng - IUBMB life, 2023 - Wiley Online Library
Abstract Fibroblast growth factor 2 (FGF2) plays an important role in tumor angiogenesis.
Humanized disulfide‐stable double‐chain antibody against fibroblast growth factor‐2 (anti …
Humanized disulfide‐stable double‐chain antibody against fibroblast growth factor‐2 (anti …
Phenotypic spectrum of FGF10-related disorders: a systematic review
K Bzdega, JA Karolak - PeerJ, 2022 - peerj.com
FGF10, as an FGFR2b-specific ligand, plays a crucial role during cell proliferation, multi-
organ development, and tissue injury repair. The developmental importance of FGF10 has …
organ development, and tissue injury repair. The developmental importance of FGF10 has …
Exploring the FGF/FGFR system in ocular tumors: new insights and perspectives
A Loda, M Turati, F Semeraro, S Rezzola… - International Journal of …, 2022 - mdpi.com
Ocular tumors are a family of rare neoplasms that develop in the eye. Depending on the type
of cancer, they mainly originate from cells localized within the retina, the uvea, or the …
of cancer, they mainly originate from cells localized within the retina, the uvea, or the …
Angiogenesis as therapeutic target in metastatic prostate cancer–narrowing the gap between bench and bedside
AG Solimando, C Kalogirou, M Krebs - Frontiers in Immunology, 2022 - frontiersin.org
Angiogenesis in metastatic castration-resistant prostate cancer (mCRPC) has been
extensively investigated as a promising druggable biological process. Nonetheless …
extensively investigated as a promising druggable biological process. Nonetheless …
Transcriptomic analysis of benign prostatic hyperplasia identifies critical pathways in prostatic overgrowth and 5‐alpha reductase inhibitor resistance
Background The medical therapy of prostatic symptoms (MTOPS) trial randomized men with
symptoms of benign prostatic hyperplasia (BPH) and followed response of treatment with a …
symptoms of benign prostatic hyperplasia (BPH) and followed response of treatment with a …
FGFR blockade by pemigatinib treats naïve and castration resistant prostate cancer
P Chiodelli, D Coltrini, M Turati, M Cerasuolo… - Cancer Letters, 2022 - Elsevier
Prostate cancer (PCa) is a leading cause of cancer mortality in the male population
commonly treated with androgen deprivation therapy (ADT) and relapsing as aggressive …
commonly treated with androgen deprivation therapy (ADT) and relapsing as aggressive …
Incidence of FGFR2 amplification and FGFR2 fusion in patients with metastatic cancer using clinical sequencing
S Hyung, B Han, J Jung, ST Kim, JY Hong… - Journal of …, 2022 - Wiley Online Library
Aberrations in the fibroblast growth factor receptor2 (FGFR2) gene, including genetic
alterations and chromosomal rearrangements, lead to the development and progression of …
alterations and chromosomal rearrangements, lead to the development and progression of …