Choice of prosthetic heart valve in adults: an update

SH Rahimtoola - Journal of the American College of Cardiology, 2010 - jacc.org
In the last 7 years, more data have reconfirmed that patients' comorbid conditions are very
important factors determining patient outcomes. Prosthetic heart valves (PHVs) that require …

Age as a risk factor for stroke in atrial fibrillation patients: implications for thromboprophylaxis

R Marinigh, GYH Lip, N Fiotti, C Giansante… - Journal of the American …, 2010 - jacc.org
The prevalence of atrial fibrillation (AF) is related to age and is projected to rise
exponentially as the population ages and the prevalence of cardiovascular risk factors …

Factors at admission associated with bleeding risk in medical patients: findings from the IMPROVE investigators

H Decousus, VF Tapson, JF Bergmann, BH Chong… - Chest, 2011 - Elsevier
Background Acutely ill, hospitalized medical patients are at risk of VTE. Despite guidelines
for VTE prevention, prophylaxis use in these patients is still poor, possibly because of fear of …

Intracranial hemorrhage among patients with atrial fibrillation anticoagulated with warfarin or rivaroxaban: the rivaroxaban once daily, oral, direct factor Xa inhibition …

GJ Hankey, SR Stevens, JP Piccini, Y Lokhnygina… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Intracranial hemorrhage (ICH) is a life-threatening complication
of anticoagulation. Methods—We investigated the rate, outcomes, and predictors of ICH in …

Canadian Cardiovascular Society atrial fibrillation guidelines 2010: prevention of stroke and systemic thromboembolism in atrial fibrillation and flutter

JA Cairns, S Connolly, S McMurtry… - Canadian Journal of …, 2011 - Elsevier
The stroke rate in atrial fibrillation is 4.5% per year, with death or permanent disability in over
half. The risk of stroke varies from under 1% to over 20% per year, related to the risk factors …

Bleeding risk assessment and management in atrial fibrillation patients

GYH Lip, F Andreotti, L Fauchier… - Thrombosis and …, 2011 - thieme-connect.com
In this executive summary of a Consensus Document from the European Heart Rhythm
Association, endorsed by the European Society of Cardiology Working Group on …

Bleeding risk assessment and management in atrial fibrillation patients: a position document from the European Heart Rhythm Association, endorsed by the European …

GYH Lip, F Andreotti, L Fauchier, K Huber, E Hylek… - Europace, 2011 - academic.oup.com
Despite the clear net clinical benefit of oral anticoagulation (OAC) in atrial fibrillation (AF)
patients at risk for stroke, major bleeding events (especially intra-cranial bleeds) may be …

Cessation of oral anticoagulation in relation to mortality and the risk of thrombotic events in patients with atrial fibrillation

P Gallego, V Roldan, F Marín, M Romera… - Thrombosis and …, 2013 - thieme-connect.com
Bleeding risk (often perceived, rather than actual) is a common reason for cessation of oral
anticoagulation with Vitamin K antagonists (VKA). We investigate clinical outcomes in a …

Bleeding risk in very old patients on vitamin K antagonist treatment: results of a prospective collaborative study on elderly patients followed by Italian Centres for …

D Poli, E Antonucci, S Testa, A Tosetto, W Ageno… - Circulation, 2011 - Am Heart Assoc
Background—Vitamin K antagonist (VKA) therapy is increasingly being used for the
prevention of venous thromboembolism and stroke in atrial fibrillation. Bleeds are the major …

Relation of the HAS-BLED bleeding risk score to major bleeding, cardiovascular events, and mortality in anticoagulated patients with atrial fibrillation

P Gallego, V Roldán, JM Torregrosa… - Circulation …, 2012 - Am Heart Assoc
Background—Stroke risk in atrial fibrillation (AF) using oral vitamin K antagonists is closely
related to bleeding risk. The HAS-BLED (hypertension, abnormal renal/liver function, stroke …