[HTML][HTML] Biological functions and clinical significance of tRNA-derived small fragment (tsRNA) in tumors: Current state and future perspectives

Q Chen, D Li, L Jiang, Y Wu, H Yuan, G Shi, F Liu… - Cancer Letters, 2024 - Elsevier
A new class of noncoding RNAs, tsRNAs are not only abundant in humans but also have
high tissue specificity. Recently, an increasing number of studies have explored the …

Exosomal circRNAs: Novel biomarkers and therapeutic targets for urinary tumors

Q Liu, S Li - Cancer Letters, 2024 - Elsevier
Exosomal circRNAs have emerged as promising biomarkers and therapeutic targets for
urinary tumors. In this review, we explored the intricate role of exosomal circRNAs in …

The role of exosomes in cancer‐related programmed cell death

X Li, Z Jing, X Li, L Liu, X Xiao, Y Zhong… - Immunological …, 2024 - Wiley Online Library
Cancer arises from the growth and division of uncontrolled erroneous cells. Programmed
cell death (PCD), or regulated cell death (RCD), includes natural processes that eliminate …

[HTML][HTML] Longitudinal detection of subcategorized CD44v6+ CTCs and circulating tumor endothelial cells (CTECs) enables novel clinical stratification and improves …

Y Wang, L Zhang, J Tan, Z Zhang, Y Liu, X Hu, B Lu… - Cancer Letters, 2023 - Elsevier
Current management of small cell lung cancer (SCLC) remains challenging. Effective
biomarkers are needed to subdivide patients presenting distinct treatment response and …

METTL3-mediated HSPA9 m6A modification promotes malignant transformation and inhibits cellular senescence by regulating exosomal mortalin protein in cervical …

K Ao, M Yin, X Lyu, Y Xiao, X Chen, S Zhong, X Wen… - Cancer Letters, 2024 - Elsevier
The role of RNA methyltransferase 3 (METTL3) in tumor progression when tethered to
aberrantly expressed oncogenes remains unknown. In especial, the correlation between …

[HTML][HTML] Exosomal non-coding RNAs: blueprint in colorectal cancer metastasis and therapeutic targets

BM Hussen, ST Abdullah, SR Abdullah… - Non-coding RNA …, 2023 - Elsevier
Colorectal cancer (CRC) is ranked as the world's third-most prevalent cancer, and metastatic
CRC considerably increases cancer-related fatalities globally. A number of complex …

Berberine protects hepatocyte from hypoxia/reoxygenation-induced injury through inhibiting circDNTTIP2

Y Zhu, J Li, P Zhang, B Peng, C Li, Y Ming, H Liu - PeerJ, 2023 - peerj.com
Background During hepatic ischemia-reperfusion injury, the excessive release of
inflammatory cytokines can activate the intracellular signal transduction cascade to induce …

Serum exosomal circCCDC66 as a potential diagnostic and prognostic biomarker for pituitary adenomas

X Yue, F Lan, W Liu - Frontiers in Oncology, 2023 - frontiersin.org
Purpose Circular RNAs (circRNAs) play an important role in tumorigenesis, and exosomal
circRNAs have the potential to be novel biomarkers for cancer diagnosis. Here, we are …

Circular RNA circHIPK2 inhibits colon cancer cells through miR-373-3p/RGMA axis

J Lun, Y Zhang, M Yu, W Zhai, L Zhu, H Liu, J Guo… - Cancer Letters, 2024 - Elsevier
Circular RNAs (circRNAs) have been implicated in cancer development. However, their
regulation, function, and underlying mechanisms of action remain unclear. We found that …

Exosomal circ_0000735 contributes to non‐small lung cancer malignant progression

S Liu, X Wu, Y Wang, Y Chen - Journal of Biochemical and …, 2024 - Wiley Online Library
Circular RNA is an important regulator for non‐small cell lung cancer (NSCLC).
Circ_0000735 has been found to be significantly overexpressed in NSCLC tissues …