Matrix metalloproteinase contribution in management of cancer proliferation, metastasis and drug targeting

NM Abdel-Hamid, SA Abass - Molecular biology reports, 2021 - Springer
Matrix metalloproteinases (MMPs) or matrixins, are members of a zinc-dependent
endopeptidase family. They cause remodeling of the extracellular matrix (ECM) leading to …

Natural product-based pharmacological studies for neurological disorders

V Puri, N Kanojia, A Sharma, K Huanbutta… - Frontiers in …, 2022 - frontiersin.org
Central nervous system (CNS) disorders and diseases are expected to rise sharply in the
coming years, partly because of the world's aging population. Medicines for the treatment of …

Activatable Probes for Ratiometric Imaging of Endogenous Biomarkers In Vivo

Q Fu, X Yang, M Wang, K Zhu, Y Wang, J Song - ACS nano, 2024 - ACS Publications
Dynamic variations in the concentration and abnormal distribution of endogenous
biomarkers are strongly associated with multiple physiological and pathological states …

Role of matrix metalloproteinases in musculoskeletal diseases

L Kumar, M Bisen, A Khan, P Kumar, SKS Patel - Biomedicines, 2022 - mdpi.com
Musculoskeletal disorders include rheumatoid arthritis, osteoarthritis, sarcopenia, injury,
stiffness, and bone loss. The prevalence of these conditions is frequent among elderly …

[HTML][HTML] Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways

J Jiang, H Pan, F Shen, Y Tan… - Neural regeneration …, 2023 - journals.lww.com
Alzheimer's disease is a progressive neurological disorder characterized by cognitive
decline and chronic inflammation within the brain. The ketogenic diet, a widely recognized …

Zinc homeostasis: an emerging therapeutic target for neuroinflammation related diseases

S Liu, N Wang, Y Long, Z Wu, S Zhou - Biomolecules, 2023 - mdpi.com
Zinc is an indispensable trace element in the human body and plays an important role in
regulating normal growth and development. Zinc homeostasis in the central nervous system …

The role of extracellular matrix in human neurodegenerative diseases

P Pintér, A Alpár - International journal of molecular sciences, 2022 - mdpi.com
The dense neuropil of the central nervous system leaves only limited space for extracellular
substances free. The advent of immunohistochemistry, soon followed by advanced …

Potential neuroprotection by Dendrobium nobile Lindl alkaloid in Alzheimer's disease models

DD Li, CQ Zheng, F Zhang, JS Shi - Neural Regeneration …, 2022 - journals.lww.com
At present, treatments for Alzheimer's disease can temporarily relieve symptoms but cannot
prevent the decline of cognitive ability and other neurodegenerative changes. Dendrobium …

Marine Pharmacology in 2019–2021: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis and Antiviral …

AMS Mayer, VA Mayer, M Swanson-Mungerson… - Marine Drugs, 2024 - mdpi.com
The current 2019–2021 marine pharmacology literature review provides a continuation of
previous reviews covering the period 1998 to 2018. Preclinical marine pharmacology …

Exploitation of marine molecules to manage alzheimer's disease

M Silva, P Seijas, P Otero - Marine Drugs, 2021 - mdpi.com
Neurodegenerative diseases are sociosanitary challenges of today, as a result of increased
average life expectancy, with Alzheimer's disease being one of the most prevalent. This …