Dysregulation of tyrosine kinase receptor (RTK) signaling pathways play important roles in
glioblastoma (GBM). However, therapies targeting these signaling pathways have not been …

In oviparous animals, the egg contains all resources required for embryonic development.
The chorioallantoic membrane (CAM) is a placenta‐like structure produced by the embryo …

Tissue and organ viability depends on the proper systemic distribution of cells, nutrients, and
oxygen through blood vessel networks. These networks arise in part via angiogenic …

One of the key challenges in engineering three-dimensional tissue constructs is the
development of a mature microvascular network capable of supplying sufficient oxygen and …

While many classes of chemotherapeutic agents exist to treat solid tumors, few can generate
a lasting response without substantial off-target toxicity despite significant scientific …

Matrix-binding isoforms and non-matrix-binding isoforms of vascular endothelial growth
factor (VEGF) are both capable of stimulating vascular remodeling, but the resulting blood …

Opioids are effective analgesics for the management of moderate to severe cancer pain.
Here we show that κ opioid receptor (KOR) agonists act as anti-angiogenic factors in tumors …

Vascular endothelial growth factor (VEGF), through its activation of cell surface receptor
tyrosine kinases including VEGFR1 and VEGFR2, is a vital regulator of stimulatory and …

Vertebrate development depends on the formation of intricate vascular networks at
numerous sites and in precise patterns; these vascular networks supply oxygen and …

This study aimed to assess the effect of gonadotrophin suppression and FSH replacement
on testicular tight junction dynamics and blood–testis barrier (BTB) organisation in vivo …