Targeting vimentin: A multifaceted approach to combatting cancer metastasis and drug resistance

A Tabatabaee, B Nafari, A Farhang, A Hariri… - Cancer and Metastasis …, 2024 - Springer
This comprehensive review explores vimentin as a pivotal therapeutic target in cancer
treatment, with a primary focus on mitigating metastasis and overcoming drug resistance …

[HTML][HTML] Preclinical Models of Neuroblastoma—Current Status and Perspectives

E Krawczyk, J Kitlińska - Cancers, 2023 - mdpi.com
Simple Summary Neuroblastoma is a pediatric tumor originating from the precursors of
sympathetic nerves. The disease is known for its high heterogeneity. Hence, developing …

Metabolic control analysis as a strategy to identify therapeutic targets, the case of cancer glycolysis

Á Marín-Hernández, E Saavedra - Biosystems, 2023 - Elsevier
The use of kinetic modeling and metabolic control analysis (MCA) to identify possible
therapeutic targets and to investigate the controlling and regulatory mechanisms in cancer …

[HTML][HTML] Precision medicine and the challenges of human complexity

DC Aron - Psychotherapy and Psychosomatics, 2023 - karger.com
It is difficult to pick up a medical journal in almost any specialty and fail to see an article
about precision medicine or precision (fill in the blank) specialty. It seems to be taking over …

Lack of cytotoxic and genotoxic effects of mPEG-silane coated iron (III) oxide nanoparticles doped with magnesium despite cellular uptake in cancerous and …

M Sikorska, M Ruzycka-Ayoush, I Rios-Mondragon… - Toxicology in Vitro, 2024 - Elsevier
Cytotoxic and genotoxic effects of novel mPEG-silane coated iron (III) oxide nanoparticles
doped with magnesium (Mg 0.1-γ-Fe 2 O 3 (mPEG-silane) 0.5) have been investigated on …

How will the identification and therapeutic intervention of genetic targets in oncology evolve for future therapy?

P Baldo, V De Re, M Garutti - Expert Opinion on Therapeutic …, 2023 - Taylor & Francis
Introduction Mapping of the human genome, together with the broad understanding of new
biomolecular pathways involved in cancer development, represents a huge dividing line for …

Advancement in Cancer Vasculogenesis Modeling through 3D Bioprinting Technology

AK Shukla, S Yoon, SO Oh, D Lee, M Ahn, BS Kim - Biomimetics, 2024 - mdpi.com
Cancer vasculogenesis is a pivotal focus of cancer research and treatment given its critical
role in tumor development, metastasis, and the formation of vasculogenic …

Recent progress and the emerging role of lncRNAs in cancer drug resistance; focusing on signaling pathways

MJ Saadh, I Rasulova, MAA Almoyad… - … -Research and Practice, 2023 - Elsevier
It is becoming more and more apparent that many of the genetic alterations associated with
cancer are located in areas that do not encode proteins. lncRNAs are a class of RNAs that …

Engineering models of head and neck and oral cancers on-a-chip

MG da Costa Sousa, SM Vignolo, CM Franca… - …, 2024 - pubs.aip.org
Head and neck cancers (HNCs) rank as the sixth most common cancer globally and result in
over 450 000 deaths annually. Despite considerable advancements in diagnostics and …

Machine Learning Radiomics Liver Function Model for Prognostic Prediction After Radical Resection of Advanced Gastric Cancer: A Retrospective Study

J Shao, Z Jiang, H Jiang, Q Ye, Y Jiang… - Annals of Surgical …, 2024 - Springer
Purpose We aimed to establish a machine learning radiomics liver function model to explore
how liver function affects the prognosis of patients with gastric cancer (GC). Methods …