The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention Workshop
Background: Increases in prescriptions of opioid medications for chronic pain have been
accompanied by increases in opioid overdoses, abuse, and other harms and uncertainty …
accompanied by increases in opioid overdoses, abuse, and other harms and uncertainty …
Opioid receptors
C Stein - Annual review of medicine, 2016 - annualreviews.org
Opioids are the oldest and most potent drugs for the treatment of severe pain. Their clinical
application is undisputed in acute (eg, postoperative) and cancer pain, but their long-term …
application is undisputed in acute (eg, postoperative) and cancer pain, but their long-term …
[HTML][HTML] CDC clinical practice guideline for prescribing opioids for pain—United States, 2022
D Dowell - MMWR. Recommendations and reports, 2022 - cdc.gov
This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …
Adult cancer pain, version 3.2019, NCCN clinical practice guidelines in oncology
RA Swarm, JA Paice, DL Anghelescu, M Are… - Journal of the National …, 2019 - jnccn.org
In recent years, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for
Adult Cancer Pain have undergone substantial revisions focusing on the appropriate and …
Adult Cancer Pain have undergone substantial revisions focusing on the appropriate and …
Opioids and cardiac arrhythmia: a literature review
Objective: One of the most important side effects of opioids is their influence on the electrical
activity of the heart. This review focusses on the effects of opioids on QT interval …
activity of the heart. This review focusses on the effects of opioids on QT interval …
The American Society of Pain and Neuroscience (ASPN) best practices and guidelines for the interventional management of cancer-associated pain
MM Aman, A Mahmoud, T Deer, D Sayed… - Journal of Pain …, 2021 - Taylor & Francis
Moderate to severe pain occurs in many cancer patients during their clinical course and may
stem from the primary pathology, metastasis, or as treatment side effects. Uncontrolled pain …
stem from the primary pathology, metastasis, or as treatment side effects. Uncontrolled pain …
Cardiac effects of opioid therapy
A Chen, MA Ashburn - Pain Medicine, 2015 - academic.oup.com
Objective The use of opioids to treat chronic pain has come under increased scrutiny, as
such use has been associated with significant risk of death, with limited data regarding the …
such use has been associated with significant risk of death, with limited data regarding the …
Opioids for chronic pain management in patients with dialysis-dependent kidney failure
DG Tobin, MB Lockwood, PL Kimmel… - Nature Reviews …, 2022 - nature.com
Chronic pain is highly prevalent among adults treated with maintenance haemodialysis (HD)
and has profound negative effects. Over four decades, research has demonstrated that 50 …
and has profound negative effects. Over four decades, research has demonstrated that 50 …
Pharmacological and behavioral treatment of opioid use disorder
M Sofuoglu, EE DeVito… - Psychiatric Research and …, 2019 - Am Psychiatric Assoc
Objective: Opioid use disorder (OUD) in the United States has surged, with an estimated 2.5
million needing treatment. The aim of this article is to provide a clinical overview of the key …
million needing treatment. The aim of this article is to provide a clinical overview of the key …