Epithelial tight junctions define the paracellular permeability of the intestinal barrier.
Molecules can cross the tight junctions via two distinct size-selective and charge-selective …

The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …

Health is usually defined as the absence of pathology. Here, we endeavor to define health
as a compendium of organizational and dynamic features that maintain physiology. The …

The gut microbiota is responsible for recovering energy from food, providing hosts with
vitamins, and providing a barrier function against exogenous pathogens. In addition, it is …

The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …

A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …

Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

Background Micro-and nanoplastic pollution has become a global environmental problem.
Nanoplastics in the environment are still hard to detect because of analysis technology …

Almost all currently available treatments for inflammatory bowel disease (IBD) act by
inhibiting inflammation, often blocking specific inflammatory molecules. However, given the …

The intestinal barrier is complex and consists of multiple layers, and it provides a physical
and functional barrier to the transport of luminal contents to systemic circulation. While the …