[HTML][HTML] Impact of anti-amyloid-β monoclonal antibodies on the pathology and clinical profile of Alzheimer's disease: a focus on aducanumab and lecanemab

M Shi, F Chu, F Zhu, J Zhu - Frontiers in aging neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most prevalent form of age-related dementia in the world,
and its main pathological features consist of amyloid-β (Aβ) plaque deposits and …

[HTML][HTML] Comprehensive review on Alzheimer's disease: causes and treatment

Z Breijyeh, R Karaman - Molecules, 2020 - mdpi.com
Alzheimer's disease (AD) is a disorder that causes degeneration of the cells in the brain and
it is the main cause of dementia, which is characterized by a decline in thinking and …

[HTML][HTML] Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology

NJ Ashton, TA Pascoal, TK Karikari, AL Benedet… - Acta …, 2021 - Springer
The quantification of phosphorylated tau in biofluids, either cerebrospinal fluid (CSF) or
plasma, has shown great promise in detecting Alzheimer's disease (AD) pathophysiology …

[HTML][HTML] Past, present and future of therapeutic strategies against amyloid-β peptides in Alzheimer's disease: A systematic review

D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing research reviews, 2021 - Elsevier
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in ageing,
affecting around 46 million people worldwide but few treatments are currently available. The …

Developing the ATX (N) classification for use across the Alzheimer disease continuum

H Hampel, J Cummings, K Blennow, P Gao… - Nature Reviews …, 2021 - nature.com
Breakthroughs in the development of highly accurate fluid and neuroimaging biomarkers
have catalysed the conceptual transformation of Alzheimer disease (AD) from the traditional …

[HTML][HTML] Amyloid beta in aging and Alzheimer's disease

U Sehar, P Rawat, AP Reddy, J Kopel… - International journal of …, 2022 - mdpi.com
Alzheimer's disease (AD), is a progressive neurodegenerative disease that affects behavior,
thinking, learning, and memory in elderly individuals. AD occurs in two forms, early onset …

[HTML][HTML] The China alzheimer report 2022

R Ren, J Qi, S Lin, X Liu, P Yin, Z Wang, R Tang… - General …, 2022 - ncbi.nlm.nih.gov
China's population has rapidly aged over the recent decades of social and economic
development as neurodegenerative disorders have proliferated, especially Alzheimer's …

[HTML][HTML] Recent advances on drug development and emerging therapeutic agents for Alzheimer's disease

T Athar, K Al Balushi, SA Khan - Molecular biology reports, 2021 - Springer
Alzheimer's disease (AD) is a neurodegenerative old age disease that is complex,
multifactorial, unalterable, and progressive in nature. The currently approved therapy …

[HTML][HTML] Amyloid-beta peptide and tau protein crosstalk in Alzheimer's disease

AR Roda, G Serra-Mir, L Montoliu-Gaya… - Neural regeneration …, 2022 - journals.lww.com
Alzheimer's disease is a neurodegenerative disease that accounts for most of the 50-million
dementia cases worldwide in 2018. A large amount of evidence supports the amyloid …

[HTML][HTML] Novel therapeutic approaches for Alzheimer's disease: an updated review

TW Yu, HY Lane, CH Lin - International journal of molecular sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease and accounts for
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …