Dystrophic cardiomyopathy—potential role of calcium in pathogenesis, treatment and novel therapies
Duchenne muscular dystrophy (DMD) is caused by defects in the DMD gene and results in
progressive wasting of skeletal and cardiac muscle due to an absence of functional …
progressive wasting of skeletal and cardiac muscle due to an absence of functional …
Focus on the lymphatic route to optimize drug delivery in cardiovascular medicine
While oral agents have been the gold standard for cardiovascular disease therapy, the new
generation of treatments is switching to other administration options that offer reduced …
generation of treatments is switching to other administration options that offer reduced …
Curcumin‐loaded nanoparticles effectively prevent T4‐induced oxidative stress in rat heart
In this study, we report the cardioprotective effect of the glycerol monooleate (GMO) based
nanocurcumin in both in vitro and in vivo conditions under a hyperthyroid state. The heart is …
nanocurcumin in both in vitro and in vivo conditions under a hyperthyroid state. The heart is …
On-demand responsive nanoplatform mediated targeting of CAFs and down-regulating mtROS-PYK2 signaling for antitumor metastasis
T Zuo, J Zhang, J Yang, R Xu, Z Hu, Z Wang… - Biomaterials …, 2021 - pubs.rsc.org
The desmoplastic tumor microenvironment (DTME), including overexpressed stromal cells
and extracellular matrix, formed the first barrier for the accumulation and penetration of …
and extracellular matrix, formed the first barrier for the accumulation and penetration of …
Animal models used in the research of nanoparticles for cardiovascular diseases
C Dong, A Ma, L Shang - Journal of Nanoparticle Research, 2021 - Springer
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide.
Tremendous progress has been made in the prevention and treatment of CVD; however …
Tremendous progress has been made in the prevention and treatment of CVD; however …
Nanotechnology-based Strategies for Molecular Imaging, Diagnosis, and Therapy of Organ Transplantation
R Sun, N Wang, S Zheng, H Wang, H Xie - Transplantation, 2024 - journals.lww.com
Organ transplantation is the preferred paradigm for patients with end-stage organ failures.
Despite unprecedented successes, complications such as immune rejection, ischemia …
Despite unprecedented successes, complications such as immune rejection, ischemia …
[HTML][HTML] Peptides derived from high voltage-gated calcium channel β subunit reduce blood pressure in rats
HK Kim, J Jun, TW Kim, D Youn - The Korean Journal of …, 2023 - synapse.koreamed.org
The β subunits of high voltage-gated calcium channels (HGCCs) are essential for optimal
channel functions such as channel gating, activation-inactivation kinetics, and trafficking to …
channel functions such as channel gating, activation-inactivation kinetics, and trafficking to …
[HTML][HTML] A dendronized polymer variant that facilitates safe delivery of a calcium channel antagonist to the heart
Therapeutic approaches for myocardial ischemia–reperfusion injury (MI) have been
ineffective due to limited bioavailability and poor specificity. We have previously shown that …
ineffective due to limited bioavailability and poor specificity. We have previously shown that …
Hepatocellular uptake of cyclodextrin‐complexed curcumin during liver preservation: A feasibility study
SA Saidi, N Meurisse, I Jochmans… - … & Drug Disposition, 2018 - Wiley Online Library
The increasing demand for donor organs and the decreasing organ quality is prompting
research toward new methods to reduce ischemia reperfusion injury (IRI). Several strategies …
research toward new methods to reduce ischemia reperfusion injury (IRI). Several strategies …
Voltage-dependent calcium channel β subunit-derived peptides reduce excitatory neurotransmission and arterial blood pressure
H Weon, J Jun, TW Kim, K Park, HK Kim, D Youn - Life Sciences, 2021 - Elsevier
Aims Voltage-dependent calcium channels (VDCCs) play an important role in various
physiological functions in the nervous system and the cardiovascular system. In L-, N-, P/Q …
physiological functions in the nervous system and the cardiovascular system. In L-, N-, P/Q …