Sickle cell disease (SCD) had first been mentioned in the literature a century ago.
Advancement in the molecular basis of the pathophysiology of the disease opens the door …

The oxygen demands of the human body require the constant circulation of blood carrying
an enormous concentration of hemoglobin (Hb). Oxygen transport depends not only on the …

Sickle cell disease is the most common hemoglobinopathy among humans. As the condition
promotes susceptibility to infections, chronic inflammation, and hypercoagulability disorders …

It is well documented that caffeic acid (3, 4‐dihydroxycinnamic acid)(CA) interacts with and
inhibits the oxidative reactions of myoglobin (Mb) and hemoglobin (Hb), and this interaction …

Sickle cell disease (SCD), a distinctive and often overlooked illness in the 21st century, is a
congenital blood disorder characterized by considerable phenotypic diversity. It comprises a …

Rare anemias (RA) are mostly hereditary disorders with low prevalence and a broad
spectrum of clinical severity, affecting different stages of erythropoiesis or red blood cell …

Background Hydroxyurea is one of the earliest drugs that showed promise in the
management of haemoglobinopathies that include β-thalassaemia and sickle cell disease …

Sickle Cell Disease (SCD) is the most prevalent inherited monogenic disease worldwide,
caused by a single nucleotide mutation in the gene for beta-globin. This results in an …

Abstract On 4 September, 2020, the US National Institutes of Health launched a new clinical
trial,“A Multicenter, Adaptive, Randomized Controlled Platform Trial of the Safety and …

Background and Aim. Hematological disorders (HD) affect millions of people annually
worldwide. Nutritional care is essential in acute or chronic HD, especially in controlling …