Biomechanical factors in atherosclerosis: mechanisms and clinical implications
Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress) …
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress) …
Role of biomechanical forces in the natural history of coronary atherosclerosis
Atherosclerosis remains a major cause of morbidity and mortality worldwide, and a thorough
understanding of the underlying pathophysiological mechanisms is crucial for the …
understanding of the underlying pathophysiological mechanisms is crucial for the …
Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques
JD Hutcheson, C Goettsch, S Bertazzo, N Maldonado… - Nature materials, 2016 - nature.com
Clinical evidence links arterial calcification and cardiovascular risk. Finite-element modelling
of the stress distribution within atherosclerotic plaques has suggested that subcellular …
of the stress distribution within atherosclerotic plaques has suggested that subcellular …
Hyperelastic energy densities for soft biological tissues: a review
Many soft tissues are naturally made of a matrix and fibres that present some privileged
directions. They are known to support large reversible deformations. The mechanical …
directions. They are known to support large reversible deformations. The mechanical …
Uniaxial tensile testing approaches for characterisation of atherosclerotic plaques
The pathological changes associated with the development of atherosclerotic plaques within
arterial vessels result in significant alterations to the mechanical properties of the diseased …
arterial vessels result in significant alterations to the mechanical properties of the diseased …
Quantification of plaque stiffness by Brillouin microscopy in experimental thin cap fibroatheroma
G Antonacci, RM Pedrigi… - Journal of the …, 2015 - royalsocietypublishing.org
Plaques vulnerable to rupture are characterized by a thin and stiff fibrous cap overlaying a
soft lipid-rich necrotic core. The ability to measure local plaque stiffness directly to quantify …
soft lipid-rich necrotic core. The ability to measure local plaque stiffness directly to quantify …
Cardiovascular calcification: current controversies and novel concepts
JL Ruiz, JD Hutcheson, E Aikawa - Cardiovascular Pathology, 2015 - Elsevier
Cardiovascular calcification is a commonly observed but incompletely understood
mechanism of increased atherosclerotic plaque instability and accelerated aortic valve …
mechanism of increased atherosclerotic plaque instability and accelerated aortic valve …
Microstructure-based biomechanics of coronary arteries in health and disease
H Chen, GS Kassab - Journal of biomechanics, 2016 - Elsevier
Coronary atherosclerosis is the major cause of mortality and disability in developed nations.
A deeper understanding of mechanical properties of coronary arteries and hence their …
A deeper understanding of mechanical properties of coronary arteries and hence their …
Cloud-based parallel machine learning for tool wear prediction
The emergence of cloud computing, industrial internet of things (IIoT), and new machine
learning techniques have shown the potential to advance prognostics and health …
learning techniques have shown the potential to advance prognostics and health …
Mechanical properties of the cranial meninges: a systematic review
The meninges are membranous tissues that are pivotal in maintaining homeostasis of the
central nervous system. Despite the importance of the cranial meninges in nervous system …
central nervous system. Despite the importance of the cranial meninges in nervous system …