The synthesis of vitellogenin and its uptake by maturing oocytes during egg maturation are
essential for successful female reproduction. These events are regulated by the juvenile …

Gametes are highly specialized cell types produced by a complex differentiation process.
Production of viable oocytes requires a series of precise and coordinated molecular events …

Steroid hormones are one of the major bioactive molecules responsible for the coordinated
regulation of biological processes in multicellular organisms. In insects, the principal steroid …

An overview is presented of the different functions of ecdysone signaling during insect
oogenesis. An extensive genetic toolkit allowed analysis with unprecedented temporal and …

Messenger RNAs (mRNAs) often contain binding sites for multiple, different microRNAs
(miRNAs). However, the biological significance of this feature is unclear, since such co …

In the germarium of the Drosophila ovary, developing germline cysts are surrounded by a
population of somatic escort cells that are known to function as the niche cells for germline …

Adult stem cells continuously undergo self-renewal and generate differentiated cells. In the
Drosophila ovary, two separate niches control germ line stem cell (GSC) self-renewal and …

Stress can be temporary or chronic, and mild or acute. Depending on its extent and severity,
cells either alter their metabolism, and adopt a new state, or die. Fluctuations in …

Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell
differentiation, and follicle survival, are regulated by the steroid hormone ecdysone. While …

Wnt signaling is a conserved regulator of stem cell behaviors, and the Drosophila
germarium has been an important model tissue for the study of stem cell maintenance …