Genes encoding SWI/SNF chromatin remodeling complex subunits are collectively mutated
in approximately 20% of human cancers. ARID1A is a SWI/SNF subunit gene whose protein …

Head and neck squamous cell carcinoma (HNSCC) includes a subset of cancers driven by
human papillomavirus (HPV). Here we use single-cell RNA-seq to profile both HPV-positive …

PURPOSE The purpose of this study was to determine if dose de-escalation from 60 to 66
Gy to 30 to 36 Gy of adjuvant radiotherapy (RT) for selected patients with human …

Human papillomaviruses (HPVs) infect the dividing cells of human epithelia and hijack the
cellular replication machinery to ensure their own propagation. In the effort to adapt the cell …

Persistent human papillomavirus (HPV) infection is the leading cause of cervical cancer.
Although the fundamental link between HPV infection and oncogenesis is established, the …

Of the~ 60 human papillomavirus (HPV) genotypes that infect the cervicovaginal epithelium,
only 12–13 “high-risk” types are well-established as causing cervical cancer, with HPV16 …

Vaginal and vulvar squamous cell carcinoma (SCC) are rare tumors that can be challenging
to treat in the recurrent or metastatic setting. We present a case series of patients with …

The actin cytoskeleton and Rho GTP ase signaling to actin assembly are prime targets of
bacterial and viral pathogens, simply because actin is involved in all motile and membrane …

Background: Cervical cancer became the third most common cancer among women, and
genome characterization of cervical cancer patients has revealed the extensive complexity …

Human leukocyte antigen (HLA)-G, a non-classical HLA-class I molecule, has a low
polymorphism frequency, restricted tissue distribution and immunoinhibitory property. HLA-G …