Hair follicle immune privilege and its collapse in alopecia areata

M Bertolini, K McElwee, A Gilhar… - Experimental …, 2020 - Wiley Online Library
Anagen stage hair follicles (HFs) exhibit “immune privilege (IP)” from the level of the bulge
downwards to the bulb. Both passive and active IP mechanisms protect HFs from …

An overview of JAK/STAT pathways and JAK inhibition in alopecia areata

M Lensing, A Jabbari - Frontiers in immunology, 2022 - frontiersin.org
Alopecia Areata (AA) is a common autoimmune disease characterized by non-scarring hair
loss ranging from patches on the scalp to complete hair loss involving the entire body …

Alopecia areata: an autoimmune disease of multiple players

P Suchonwanit, C Kositkuljorn… - ImmunoTargets and …, 2021 - Taylor & Francis
Alopecia areata (AA) is an autoimmune disease of the hair follicles. It is characterized by a
well-defined non-scarring alopecic patch or patches that may extend to the entire scalp or …

Alopecia areata: current treatments and new directions

D Dahabreh, S Jung, Y Renert-Yuval, J Bar… - American Journal of …, 2023 - Springer
Alopecia areata is an autoimmune hair loss disease that is non-scarring and is
characterized by chronic inflammation at the hair follicle level. Clinically, patients' …

Frontiers in alopecia areata pathobiology research

A Gilhar, R Laufer-Britva, A Keren, R Paus - Journal of Allergy and Clinical …, 2019 - Elsevier
This current review explores selected and as yet insufficiently investigated frontiers in
current alopecia areata (AA) pathobiology research, with an emphasis on potential “new” …

Inhibition of T-cell activity in alopecia areata: Recent developments and new directions

T Passeron, B King, J Seneschal, M Steinhoff… - Frontiers in …, 2023 - frontiersin.org
Alopecia areata (AA) is an autoimmune disease that has a complex underlying
immunopathogenesis characterized by nonscarring hair loss ranging from small bald …

Inflammatory loops in the epithelial–immune microenvironment of the skin and skin appendages in chronic inflammatory diseases

T Dainichi, M Iwata - Frontiers in Immunology, 2023 - frontiersin.org
The epithelial–immune microenvironment (EIME) of epithelial tissues has five common
elements:(1) microbial flora,(2) barrier,(3) epithelial cells,(4) immune cells, and (5) …

[HTML][HTML] Immunopathogenesis of alopecia areata

JM Richmond - Current Research in Immunology, 2021 - Elsevier
Alopecia areata (AA) is an autoimmune disorder resulting in hair loss. It has numerous
variants or patterns, including diffuse type, patchy type, AA totalis, AA universalis, and more …

Elevated serum level of interleukin‐15 in vitiligo patients and its correlation with disease severity but not activity

MA Atwa, SMM Ali, N Youssef… - Journal of Cosmetic …, 2021 - Wiley Online Library
Background Vitiligo is a common acquired disorder of depigmentation. Its pathogenesis
entails a T helper (Th) 1‐cytotoxic T (cT) lymphocytes mediated autoimmune melanocyte …

Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata

Ö Aşkın, SN Yücesoy, E Coşkun, B Engin… - Anais brasileiros de …, 2021 - SciELO Brasil
Background: Alopecia areata (AA) is a hair disease that causes hair loss without scarring.
The etiopathogenesis of AA has not been fully understood yet. Objective: To determine …