New set of isobaric labeling reagents for quantitative 16Plex proteomics
X Ning, Q Li, J Zi, Z Mei, J Liu, Y Zhang, M Bi… - Analytical …, 2023 - ACS Publications
Peptide labeling by isobaric tags is a powerful approach for the relative quantitative analysis
of proteomes in multiple groups. There has been a revolution in the innovation of new …
of proteomes in multiple groups. There has been a revolution in the innovation of new …
Proteomic Discovery and Array-Based Validation of Biomarkers from Urinary Exosome by Supramolecular Probe
X Feng, S Jia, MM Ali, G Zhang, D Li… - Journal of Proteome …, 2023 - ACS Publications
Exosomes are nanoscale, membrane-enclosed vesicles with contents similar to their parent
cells, which are rich in potential biomarkers. Urine, as a noninvasive sampling body fluid …
cells, which are rich in potential biomarkers. Urine, as a noninvasive sampling body fluid …
Vitamin D Receptor Activation Reduces Hepatic Inflammation via Enhancing Macrophage Autophagy in Cholestatic Mice
T Wen, J Xie, L Ma, Z Hao, W Zhang, T Wu… - The American Journal of …, 2024 - Elsevier
Macrophage autophagy dysfunction aggravates liver injury by activating inflammasomes,
which can cleave pro-IL-1β to its active, secreted form. We investigated whether the vitamin …
which can cleave pro-IL-1β to its active, secreted form. We investigated whether the vitamin …
Screening of novel biomarkers for acute kidney transplant rejection using DIA‐MS based proteomics
C Wang, G Feng, J Zhao, Y Xu, Y Li… - PROTEOMICS …, 2024 - Wiley Online Library
Background Kidney transplantation is the preferred treatment for patients with end‐stage
renal disease. However, acute rejection poses a threat to the graft long‐term survival. The …
renal disease. However, acute rejection poses a threat to the graft long‐term survival. The …
Myeloid cells in alcoholic liver diseases: Mechanism and prospect
W Xu, M Wu, B Chen, H Wang - Frontiers in Immunology, 2022 - frontiersin.org
Alcoholic liver disease (ALD) is a leading chronic liver disease in which immune cells play a
vital role. Myeloid cells have been extensively studied in ALD, including granulocytes …
vital role. Myeloid cells have been extensively studied in ALD, including granulocytes …
[HTML][HTML] Molecular interactions in an holobiont-pathogen model: Integromics in gilthead seabream infected with Sparicotyle chrysophrii
S Toxqui-Rodríguez, E Riera-Ferrer, R Del Pozo… - Aquaculture, 2024 - Elsevier
The gill ectoparasite Sparicotyle chrysophrii is the major parasitic pathogen in gilthead
seabream (Sparus aurata) aquaculture with limited management and treatment strategies. In …
seabream (Sparus aurata) aquaculture with limited management and treatment strategies. In …
Multidimensional Interactive Cascading Nanochips for Detection of Multiple Liver Diseases via Precise Metabolite Profiling
Z Li, W Peng, J Zhou, S Shui, Y Liu, T Li… - Advanced …, 2024 - Wiley Online Library
It is challenging to detect and differentiate multiple diseases with high complexity/similarity
from the same organ. Metabolic analysis based on nanomatrix‐assisted laser …
from the same organ. Metabolic analysis based on nanomatrix‐assisted laser …
Advancing alcohol-related liver disease: from novel biomarkers to refining selection for liver transplantation
JP Arab, R Bataller - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
Key advances Non-invasive plasma proteomics from patients with alcohol-related liver
disease (ALD) can be used to identify prognostic biomarkers and potential targets for …
disease (ALD) can be used to identify prognostic biomarkers and potential targets for …
Non‐invasive markers of inflammation in alcohol‐associated liver disease: A scoping review
Clinical manifestations of liver inflammation in alcohol‐associated liver disease (ALD) can
range from asymptomatic to severe alcoholic hepatitis. While biopsy is the gold standard for …
range from asymptomatic to severe alcoholic hepatitis. While biopsy is the gold standard for …
[HTML][HTML] Development of immune‐related cell‐based machine learning for disease progression and prognosis of alcoholic liver disease
X Zhang, X Feng, Q Huai, C Zhu, Y Sun… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Dear Editor, Immune-related cell (IRCs)-based machine learning (ML) models, including
random forest (RF), multilayer perceptron (MLP), generalised linear model (GLM) and …
random forest (RF), multilayer perceptron (MLP), generalised linear model (GLM) and …