Designing microbial cell factories for the production of chemicals
The sustainable production of chemicals from renewable, nonedible biomass has emerged
as an essential alternative to address pressing environmental issues arising from our heavy …
as an essential alternative to address pressing environmental issues arising from our heavy …
[HTML][HTML] Synthetic biology strategies for microbial biosynthesis of plant natural products
Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …
[HTML][HTML] CRISPR-Cpf1 assisted genome editing of Corynebacterium glutamicum
Y Jiang, F Qian, J Yang, Y Liu, F Dong, C Xu… - Nature …, 2017 - nature.com
Corynebacterium glutamicum is an important industrial metabolite producer that is difficult to
genetically engineer. Although the Streptococcus pyogenes (Sp) CRISPR-Cas9 system has …
genetically engineer. Although the Streptococcus pyogenes (Sp) CRISPR-Cas9 system has …
Metabolic engineering advances and prospects for amino acid production
VF Wendisch - Metabolic engineering, 2020 - Elsevier
Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …
Amino acids production focusing on fermentation technologies–A review
M D'Este, M Alvarado-Morales, I Angelidaki - Biotechnology advances, 2018 - Elsevier
Amino acids are attractive and promising biochemicals with market capacity requirements
constantly increasing. Their applicability ranges from animal feed additives, flavour …
constantly increasing. Their applicability ranges from animal feed additives, flavour …
Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being
S Wolf, J Becker, Y Tsuge, H Kawaguchi… - Essays in …, 2021 - portlandpress.com
The soil microbe Corynebacterium glutamicum is a leading workhorse in industrial
biotechnology and has become famous for its power to synthetise amino acids and a range …
biotechnology and has become famous for its power to synthetise amino acids and a range …
[HTML][HTML] Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications
Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …
[HTML][HTML] Microbial production of ectoine and hydroxyectoine as high-value chemicals
M Liu, H Liu, M Shi, M Jiang, L Li, Y Zheng - Microbial Cell Factories, 2021 - Springer
Ectoine and hydroxyectoine as typical representatives of compatible solutes are not only
essential for extremophiles to survive in extreme environments, but also widely used in …
essential for extremophiles to survive in extreme environments, but also widely used in …
Biosystem design of Corynebacterium glutamicum for bioproduction
Highlights•Corynebacterium glutamicum has been used for many applications beyond
amino acids.•Economical, high-quality genome assemblies foster development of non-type …
amino acids.•Economical, high-quality genome assemblies foster development of non-type …
[HTML][HTML] The role of the human microbiome in the pathogenesis of pain
K Ustianowska, Ł Ustianowski, F Machaj… - International Journal of …, 2022 - mdpi.com
Understanding of the gut microbiome's role in human physiology developed rapidly in recent
years. Moreover, any alteration of this microenvironment could lead to a pathophysiological …
years. Moreover, any alteration of this microenvironment could lead to a pathophysiological …