Fluid overload and mortality in adult critical care patients—a systematic review and meta-analysis of observational studies

AS Messmer, C Zingg, M Müller, JL Gerber… - Critical care …, 2020 - journals.lww.com
Objective: Fluid administration in combination with the increase in vasopermeability induced
by critical illness often results in significant fluid overload in critically ill patients. Recent …

Principles of fluid management and stewardship in septic shock: it is time to consider the four D's and the four phases of fluid therapy

MLNG Malbrain, N Van Regenmortel, B Saugel… - Annals of intensive …, 2018 - Springer
In patients with septic shock, the administration of fluids during initial hemodynamic
resuscitation remains a major therapeutic challenge. We are faced with many open …

Paradigms of acute kidney injury in the intensive care setting

JA Kellum, JR Prowle - Nature Reviews Nephrology, 2018 - nature.com
Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies,
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …

Intraoperative hypotension and postoperative outcomes: a meta-analysis of randomised trials

F D'Amico, EV Fominskiy, S Turi, A Pruna… - British Journal of …, 2023 - Elsevier
Introduction Intraoperative hypotension is associated with adverse postoperative outcomes;
however these findings are supported only by observational studies. The aim of this meta …

The use of venous Doppler to predict adverse kidney events in a general ICU cohort

R Spiegel, W Teeter, S Sullivan, K Tupchong… - Critical care, 2020 - Springer
Abstract Background Changes in Doppler flow patterns of hepatic veins (HV), portal vein
(PV) and intra-renal veins (RV) reflect right atrial pressure and venous congestion; the …

Acute kidney injury in the ICU: from injury to recovery: reports from the 5th Paris International Conference

R Bellomo, C Ronco, RL Mehta, P Asfar… - Annals of intensive …, 2017 - Springer
Abstract The French Intensive Care Society organized its yearly Paris International
Conference in intensive care on June 18–19, 2015. The main purpose of this meeting is to …

[HTML][HTML] Diagnosis of fluid overload: from conventional to contemporary concepts

A Koratala, C Ronco, A Kazory - Cardiorenal Medicine, 2022 - karger.com
Fluid overload has been associated with morbidity and mortality in various clinical scenarios
including heart failure and critical illness. It exerts pathologic sequelae in almost all the …

Cardiorenal syndrome in acute kidney injury

L Di Lullo, PB Reeves, A Bellasi, C Ronco - Seminars in nephrology, 2019 - Elsevier
Varying degrees of cardiac and kidney dysfunction commonly are observed in hospitalized
patients. As a demonstration of the significant interplay between the heart and kidneys …

Acute kidney injury in septic patients treated by selected nephrotoxic antibiotic agents—pathophysiology and biomarkers—a review

N Petejova, A Martinek, J Zadrazil, M Kanova… - International journal of …, 2020 - mdpi.com
Acute kidney injury is a common complication in critically ill patients with sepsis and/or
septic shock. Further, some essential antimicrobial treatment drugs are themselves …

[HTML][HTML] Higher versus lower blood pressure targets after cardiac arrest: Systematic review with individual patient data meta-analysis

V Niemelä, F Siddiqui, K Ameloot, M Reinikainen… - Resuscitation, 2023 - Elsevier
Purpose Guidelines recommend targeting mean arterial pressure (MAP)> 65 mmHg in
patients after cardiac arrest (CA). Recent trials have studied the effects of targeting a higher …