Viral vector-based gene therapy

X Li, Y Le, Z Zhang, X Nian, B Liu, X Yang - International Journal of …, 2023 - mdpi.com
Gene therapy is a technique involving the modification of an individual's genes for treating a
particular disease. The key to effective gene therapy is an efficient carrier delivery system …

Multiplex genome editing to construct cellulase engineered Saccharomyces cerevisiae for ethanol production from cellulosic biomass

Y Dixit, P Yadav, AK Sharma, P Pandey… - … and Sustainable Energy …, 2023 - Elsevier
The production of biofuels from cellulosic biomass has emerged as an appealing alternative
to fossil fuels. However, the recalcitrance of cellulose poses a challenge to converting it into …

Genome editing via non-viral delivery platforms: current progress in personalized cancer therapy

T Lan, H Que, M Luo, X Zhao, X Wei - Molecular Cancer, 2022 - Springer
Cancer is a severe disease that substantially jeopardizes global health. Although
considerable efforts have been made to discover effective anti-cancer therapeutics, the …

A new age of precision gene therapy

A Schambach, CJ Buchholz, R Torres-Ruiz, K Cichutek… - The Lancet, 2023 - thelancet.com
Gene therapy has become a clinical reality as market-approved advanced therapy medicinal
products for the treatment of distinct monogenetic diseases and B-cell malignancies. This …

Cell and gene therapy for anemia: hematopoietic stem cells and gene editing

D Anurogo, N Yuli Prasetyo Budi, MH Thi Ngo… - International journal of …, 2021 - mdpi.com
Hereditary anemia has various manifestations, such as sickle cell disease (SCD), Fanconi
anemia, glucose-6-phosphate dehydrogenase deficiency (G6PDD), and thalassemia. The …

You can't keep a bad idea down: Dark history, death, and potential rebirth of eugenics

M Liscum, ML Garcia - The Anatomical Record, 2022 - Wiley Online Library
Abstract “Be careful what you wish for”: This adage guides both how this project came to life,
and how the topic covered in this review continues to unfold. What began as talks between …

Development of new genome editing tools for the treatment of hyperlipidemia

G Preta - Cells, 2023 - mdpi.com
Hyperlipidemia is a medical condition characterized by high levels of lipids in the blood. It is
often associated with an increased risk of cardiovascular diseases such as heart attacks and …

Application of Nanotechnology in Plant Genetic Engineering

K Wu, C Xu, T Li, H Ma, J Gong, X Li, X Sun… - International Journal of …, 2023 - mdpi.com
The ever-increasing food requirement with globally growing population demands advanced
agricultural practices to improve grain yield, to gain crop resilience under unpredictable …

ReptiLearn: An automated home cage system for behavioral experiments in reptiles without human intervention

T Eisenberg, M Shein-Idelson - Plos Biology, 2024 - journals.plos.org
Understanding behavior and its evolutionary underpinnings is crucial for unraveling the
complexities of brain function. Traditional approaches strive to reduce behavioral complexity …

CRISPR-Cas9 mediated understanding of plants' abiotic stress-responsive genes to combat changing climatic patterns

MW Choudry, R Riaz, P Nawaz, M Ashraf, B Ijaz… - Functional & Integrative …, 2024 - Springer
Multiple abiotic stresses like extreme temperatures, water shortage, flooding, salinity, and
exposure to heavy metals are confronted by crop plants with changing climatic patterns …