[HTML][HTML] CRISPR-cas9 screening identified lethal genes enriched in Hippo kinase pathway and of predictive significance in primary low-grade glioma
M Mijiti, A Maimaiti, X Chen, M Tuersun, M Dilixiati… - Molecular …, 2023 - Springer
Background Low-grade gliomas (LGG) are a type of brain tumor that can be lethal, and it is
essential to identify genes that are correlated with patient prognosis. In this study, we aimed …
essential to identify genes that are correlated with patient prognosis. In this study, we aimed …
[HTML][HTML] Integrated single-cell and bulk RNA-seq analysis identifies a prognostic T-cell signature in colorectal cancer
P Cui, H Wang, Z Bai - Scientific Reports, 2024 - nature.com
Colorectal cancer (CRC) is a major contributor to global morbidity and mortality,
necessitating more effective therapeutic approaches. T cells, prominent in the tumor …
necessitating more effective therapeutic approaches. T cells, prominent in the tumor …
Transcriptome data‐based status of PI3K/AKT/mTOR pathway indicates heterogeneity and immune modulation in patients with pancreatic ductal adenocarcinoma
P Xie, SY Tan, HF Li, HD Tang… - The Journal of Gene …, 2024 - Wiley Online Library
Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer with limited
treatment options. The PI3K/AKT/mTOR pathway is commonly activated in PDAC and plays …
treatment options. The PI3K/AKT/mTOR pathway is commonly activated in PDAC and plays …
[HTML][HTML] Wnt signaling pathway-derived score for predicting therapeutic resistance and tumor microenvironment in lung adenocarcinoma
H Zhou, L Zhao - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer.
Due to tumor heterogeneity, understanding the pathological mechanism of tumor …
Due to tumor heterogeneity, understanding the pathological mechanism of tumor …
[HTML][HTML] Identification of prognostic and diagnostic signatures for cancer and acute myocardial infarction: multi-omics approaches for deciphering heterogeneity to …
N Yuan, HH Pan, YS Liang, HL Hu, CL Zhai… - Frontiers in …, 2023 - frontiersin.org
Patients diagnosed with cancer face an increased risk of cardiovascular events in the short
term, while those experiencing acute myocardial infarction (AMI) have a higher incidence of …
term, while those experiencing acute myocardial infarction (AMI) have a higher incidence of …
Overexpression of SLC2A1, ALDOC, and PFKFB4 in the glycolysis pathway drives strong drug resistance in 3D HeLa tumor cell spheroids
T Wang, X Wang, X Zheng, Z Guo… - Biotechnology …, 2024 - Wiley Online Library
The 3D multicellular tumor spheroid (MTS) model exhibits enhanced fidelity in replicating
the tumor microenvironment and demonstrates exceptional resistance to clinical drugs …
the tumor microenvironment and demonstrates exceptional resistance to clinical drugs …
[HTML][HTML] Identification of the key genes and mechanisms associated with transcatheter arterial chemoembolisation refractoriness in hepatocellular carcinoma
JZ Huang, JD Li, G Chen, RQ He - World Journal of Clinical …, 2024 - ncbi.nlm.nih.gov
Identification of the key genes and mechanisms associated with transcatheter arterial
chemoembolisation refractoriness in hepatocellular carcinoma - PMC Back to Top Skip to …
chemoembolisation refractoriness in hepatocellular carcinoma - PMC Back to Top Skip to …
Analysis of the safety and effectiveness of TACE combined with targeted immunotherapy in the treatment of intermediate and advanced hepatocellular carcinoma
W Liu, Z Xie, K Shen, L Jiang, C Liu, Y Ge, J Yu, W Jia… - Medical Oncology, 2023 - Springer
To evaluate the effectiveness and safety of transarterial chemoembolization (TACE)
combined with immune and targeted therapy in unresectable hepatocellular carcinoma …
combined with immune and targeted therapy in unresectable hepatocellular carcinoma …
[HTML][HTML] Immune-related gene signature to predict TACE refractoriness in patients with hepatocellular carcinoma based on artificial neural network
Q Xu, C Wang, G Yin - Frontiers in Genetics, 2023 - frontiersin.org
Background: Transarterial chemoembolization (TACE) is the standard treatment option for
intermediate-stage hepatocellular carcinoma (HCC), while response varies among patients …
intermediate-stage hepatocellular carcinoma (HCC), while response varies among patients …
[PDF][PDF] 肝癌TACE 抵抗的预测及后续治疗研究进展
杨俊辉， 夏景林 - 肝胆胰外科杂志, 2023 - gdy.qk.wmu.edu.cn
肝动脉化疗栓塞(TACE) 是中期肝细胞癌(HCC) 的标准治疗方案, 部分患者无法在重复的TACE
疗程中获益, 这种状况被称为“TACE 抵抗”. TACE 抵抗发生的原因尚未完全阐明, TACE …
疗程中获益, 这种状况被称为“TACE 抵抗”. TACE 抵抗发生的原因尚未完全阐明, TACE …