[HTML][HTML] Genetics of multiple endocrine neoplasia type 1 syndrome: what's new and what's old
A Falchetti - F1000Research, 2017 - ncbi.nlm.nih.gov
Despite its identification in 1997, the functions of the MEN1 gene—the main gene underlying
multiple endocrine neoplasia type 1 syndrome—are not yet fully understood. In addition …
multiple endocrine neoplasia type 1 syndrome—are not yet fully understood. In addition …
[HTML][HTML] 15 years of paraganglioma: imaging and imaging-based treatment of pheochromocytoma and paraganglioma
F Castinetti, A Kroiss, R Kumar… - Endocrine-related …, 2015 - erc.bioscientifica.com
Although anatomic imaging to assess the precise localization of pheochromocytomas/
paragangliomas (PHEOs/PGLs) is unavoidable before any surgical intervention on these …
paragangliomas (PHEOs/PGLs) is unavoidable before any surgical intervention on these …
Multiple endocrine neoplasia syndrome type 1: institution, management, and data analysis of a nationwide multicenter patient database
F Giusti, L Cianferotti, F Boaretto, F Cetani, F Cioppi… - Endocrine, 2017 - Springer
Objective The aim of this study was to integrate European epidemiological data on patients
with multiple endocrine neoplasia type 1 by creating an Italian registry of this syndrome …
with multiple endocrine neoplasia type 1 by creating an Italian registry of this syndrome …
Long-term natural course of small nonfunctional pancreatic neuroendocrine tumors in MEN1—results from the Dutch MEN1 Study Group
CRC Pieterman, JM De Laat, JWR Twisk… - The Journal of …, 2017 - academic.oup.com
Background Pancreatic neuroendocrine tumors (pNETs) are highly prevalent in patients with
multiple endocrine neoplasia type 1 (MEN1), and metastatic disease is an important cause …
multiple endocrine neoplasia type 1 (MEN1), and metastatic disease is an important cause …
Genetic and clinical features of multiple endocrine neoplasia types 1 and 2
C Romei, E Pardi, F Cetani, R Elisei - Journal of oncology, 2012 - Wiley Online Library
Multiple endocrine neoplasia (MEN) are clinical inherited syndromes affecting different
endocrine glands. Three different patterns of MEN syndromes can occur (MEN 1, MEN 2A …
endocrine glands. Three different patterns of MEN syndromes can occur (MEN 1, MEN 2A …
[HTML][HTML] Phenotypes associated with MEN1 syndrome: a focus on genotype-phenotype correlations
Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant inherited tumor
syndrome, associated with parathyroid, pituitary, and gastro-entero-pancreatic (GEP) …
syndrome, associated with parathyroid, pituitary, and gastro-entero-pancreatic (GEP) …
MEN1, MEN4, and carney complex: pathology and molecular genetics
MH Schernthaner-Reiter, G Trivellin… - Neuroendocrinology, 2016 - karger.com
Pituitary adenomas are a common feature of a subset of endocrine neoplasia syndromes,
which have otherwise highly variable disease manifestations. We provide here a review of …
which have otherwise highly variable disease manifestations. We provide here a review of …
Multiple endocrine neoplasia type 1
Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited syndrome caused by
inactivating heterozygote mutations of the MEN1 gene affecting parathyroid glands …
inactivating heterozygote mutations of the MEN1 gene affecting parathyroid glands …
Twenty years of menin: emerging opportunities for restoration of transcriptional regulation in MEN1
KMA Dreijerink, HTM Timmers… - Endocrine-related …, 2017 - erc.bioscientifica.com
Since the discovery of the multiple endocrine neoplasia type 1 (MEN1) gene in 1997,
elucidation of the molecular function of its protein product, menin, has been a challenge …
elucidation of the molecular function of its protein product, menin, has been a challenge …
Higher risk of aggressive pancreatic neuroendocrine tumors in MEN1 patients with MEN1 mutations affecting the CHES1 interacting MENIN domain
DK Bartsch, EP Slater, M Albers… - The Journal of …, 2014 - academic.oup.com
Context: Sixty to 80% of multiple endocrine neoplasia type 1 (MEN1) patients develop
pancreatic neuroendocrine neoplasias (pNENs), which reveal an aggressive behavior in …
pancreatic neuroendocrine neoplasias (pNENs), which reveal an aggressive behavior in …